Protein-directed synthesis of Bi2S3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract
文献类型：期刊论文
| 作者 | Yong, Y ; Zu, Y; Zhao YL(赵宇亮); Gu ZJ(谷战军); Zhao F(赵峰); Yan L(晏亮); Yin WY(尹文艳); Dong XH(董兴华); Yu J(余杰); Zhang X(张潇)
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| 刊名 | RSC ADVANCES
 |
| 出版日期 | 2017 |
| 卷号 | 7期号:28页码:17505-17513 |
| ISSN号 | 2046-2069 |
| DOI | 10.1039/c7ra01526g |
| 文献子类 | Article |
| 英文摘要 | Non-invasive imaging modalities such as computed tomography are often used for diagnosis and assessment of gastrointestinal (GI) disease status over the long-term. The physiology of the GI tract can be assessed with contrast agents. Here, we present common protein (bovine serum albumin, BSA) stabilized bismuth sulfide nanoparticles with robust X-ray attenuation. Under the optimal conditions, this agent can outline the anatomy of the mouse GI tract on 3D computed tomography imaging, with the real-time and non-invasive visualization of nanoparticle distribution and the GI tract. Moreover, the investigation on long-term toxicity and biodistribution of these nanoparticles after oral administration indicate their overall safety. This is a promising agent for GI visualization and disease diagnosis. |
| WOS关键词 | BISMUTH SULFIDE NANOPARTICLES ; LARGE-SCALE SYNTHESIS ; COMPUTED-TOMOGRAPHY ; IN-VIVO ; ASSISTED SYNTHESIS ; NANODOTS ; NANORODS ; CANCER ; DELIVERY ; THERAPY |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000398802000068 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/284961]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Yong, Y,Zu, Y,Zhao YL,et al. Protein-directed synthesis of Bi2S3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract[J]. RSC ADVANCES,2017,7(28):17505-17513. |
| APA | Yong, Y.,Zu, Y.,赵宇亮.,谷战军.,赵峰.,...&Zhang, X.(2017).Protein-directed synthesis of Bi2S3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract.RSC ADVANCES,7(28),17505-17513. |
| MLA | Yong, Y,et al."Protein-directed synthesis of Bi2S3 nanoparticles as an efficient contrast agent for visualizing the gastrointestinal tract".RSC ADVANCES 7.28(2017):17505-17513. |
入库方式： OAI收割
来源：高能物理研究所
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