Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers
文献类型：期刊论文
| 作者 | Ge WQ(葛文奇); Wu HC(吴海臣) ; Yao, ZY; Ge, WQ; Zhang, L; Wu, HC; Qiao, YD; Yao ZY(姚志轶)
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| 刊名 | ORGANIC & BIOMOLECULAR CHEMISTRY
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| 出版日期 | 2017 |
| 卷号 | 15期号:12页码:2569-2574 |
| ISSN号 | 1477-0520 |
| DOI | 10.1039/c7ob00115k |
| 文献子类 | Article |
| 英文摘要 | We have developed a ratiometric sensor based on polyelectrolyte- induced pyrene excimers for the rapid and visual detection of heparin in aqueous media. This sensor has a simple preparation method, fast response, low cost, and high sensitivity and selectivity. As a complementary strategy for the detection of heparin based on the formation of pyrene excimers, this approach could identify heparin specifically over chondroitin sulphate, which is the major interferent in most sensing systems for the detection of heparin. The detection limit of this approach can be as low as 0.14 mu M using fluorescence measurements. To the best of our knowledge, this is among the lowest LOD for the detection of heparin reported in the literature. It enables the rapid and visual detection of heparin both in buffered solution and serum samples. |
| 电子版国际标准刊号 | 1477-0539 |
| WOS关键词 | ELECTROCHEMICAL SENSOR ; NANOPARTICLES ; PROTAMINE ; ASSAY |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:000397948000013 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/285187]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Ge WQ,Wu HC,Yao, ZY,et al. Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers[J]. ORGANIC & BIOMOLECULAR CHEMISTRY,2017,15(12):2569-2574. |
| APA | 葛文奇.,吴海臣.,Yao, ZY.,Ge, WQ.,Zhang, L.,...&姚志轶.(2017).Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers.ORGANIC & BIOMOLECULAR CHEMISTRY,15(12),2569-2574. |
| MLA | 葛文奇,et al."Rapid and visual detection of heparin based on the disassembly of polyelectrolyte-induced pyrene excimers".ORGANIC & BIOMOLECULAR CHEMISTRY 15.12(2017):2569-2574. |
入库方式： OAI收割
来源：高能物理研究所
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