Comparison of Diagnostic Performance of Three-Dimensional Positron Emission Mammography versus Whole Body Positron Emission Tomography in Breast Cancer
文献类型：期刊论文
| 作者 | Li, L; Wang, M; Ma, WC; Xu, WG; Ma, YC; Liu, JT; Zhang, J; Liu, PF ; Gu, XY; Su, YS
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| 刊名 | CONTRAST MEDIA & MOLECULAR IMAGING
 |
| 出版日期 | 2017 |
| 页码 | 5438395 |
| ISSN号 | 1555-4309 |
| DOI | 10.1155/2017/5438395 |
| 文献子类 | Article |
| 英文摘要 | Objective. To compare the diagnostic performance of three-dimensional (3D) positron emission mammography (PEM) versus whole body positron emission tomography (WBPET) for breast cancer. Methods. A total of 410 women with normal breast or benign or highly suspicious malignant tumors were randomized at 1 : 1 ratio to undergo 3D-PEM followed by WBPET or WBPET followed by 3D-PEM. Lumpectomy or mastectomy was performed on eligible participants after the scanning. Results. The sensitivity and specificity of 3D-PEM were 92.8% and 54.5%, respectively. WBPET showed a sensitivity of 95.7% and specificity of 56.8%. After exclusion of the patients with lesions beyond the detecting range of the 3D-PEM instrument, 3D-PEM showed higher sensitivity thanWBPET(97.0% versus 95.5%, P = 0.913), particularly for small lesions (< 1 cm) (72.0% versus 60.0%, P = 0.685). Conclusions. The 3D-PEM appears more sensitive to small lesions thanWBPET but may fail to detect lesions that are beyond the detecting range. This study was approved by the Ethics Committee (E2012052) at the Tianjin Medical University Cancer Institute and Hospital (Tianjin, China). The instrument positron emission mammography (PEMi) was approved by China State Food and Drug Administration under the registration number 20153331166. |
| 电子版国际标准刊号 | 1555-4317 |
| WOS关键词 | NEOADJUVANT CHEMOTHERAPY ; FDG-PET ; METAANALYSIS ; SENSITIVITY ; MANAGEMENT |
| WOS研究方向 | Radiology, Nuclear Medicine & Medical Imaging |
| 语种 | 英语 |
| WOS记录号 | WOS:000405858800001 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/285238]  |
| 专题 | 高能物理研究所_核技术应用研究中心 中国科学院高能物理研究所_中国散裂中子源 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Li, L,Wang, M,Ma, WC,et al. Comparison of Diagnostic Performance of Three-Dimensional Positron Emission Mammography versus Whole Body Positron Emission Tomography in Breast Cancer[J]. CONTRAST MEDIA & MOLECULAR IMAGING,2017:5438395. |
| APA | Li, L.,Wang, M.,Ma, WC.,Xu, WG.,Ma, YC.,...&顾笑悦.(2017).Comparison of Diagnostic Performance of Three-Dimensional Positron Emission Mammography versus Whole Body Positron Emission Tomography in Breast Cancer.CONTRAST MEDIA & MOLECULAR IMAGING,5438395. |
| MLA | Li, L,et al."Comparison of Diagnostic Performance of Three-Dimensional Positron Emission Mammography versus Whole Body Positron Emission Tomography in Breast Cancer".CONTRAST MEDIA & MOLECULAR IMAGING (2017):5438395. |
入库方式： OAI收割
来源：高能物理研究所
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