The ethanol extract of honeysuckle stem modulates the innate immunity of Chinese mitten crab Eriocheir sinensis against Aeromonas hydrophila
文献类型：期刊论文
| 作者 | Zhao, Zhilong1; Zhang, Haijuan1; Wang, Mengqiang2 ; Zhang, Chun1; Kuang, Pengqun1; Zhou, Zhi3; Zhang, Guizhi1; Wang, Zhen1; Zhang, Bianbian1; Shi, Xiaowei1
|
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2018-11-01 |
| 卷号 | 82页码:304-311 |
| 关键词 | Honeysuckle stem Eriocheir sinensis Aeromonas hydrophila Immunomodulation |
| ISSN号 | 1050-4648 |
| DOI | 10.1016/j.fsi.2018.08.035 |
| 通讯作者 | Wang, Zhen(wangzhen@lyu.edu.cn) ; Shi, Xiaowei(shixiaowei@lyu.edu.cn) |
| 英文摘要 | Honeysuckle stem had been used as feed additives to modulate immunity in breeding industry, which was limited in the aquaculture field. In this study, the immunomodulation of honeysuckle stem ethanol extract (designed as HSE) on Chinese mitten crab Eriocheir sinensis was detected. The crabs fed with HSE diets for 30 days had higher level of the total haemocyte count (HTC), lysozyme activity and PO activity (P < 0.05), and had no obvious affect on the phagocytic activity, NO and TNF-alpha level. When challenged with Aeromonas hydrophila (1.0 x 10(7) colony-forming units), HSE exhibited weak antibacterial activity against A. hydrophila and increased survival rate of crabs. The decreasing of THC and the increasing of TNF-alpha concentration, EsCaspase and EsLITAF mRNA expression level were all inhibited significantly by HSE treatment (P < 0.05), when the crabs were challenged by A. hydrophila. Moreover, the following immune parameters of crabs were enhanced by HSE treatment after A. hydrophila infection, including the rising of phagocytosis index and phagocytic rate of haemocyte, the rising of lysozyme, PO, NOS activities and nitric oxide concentration (P < 0.05). Therefore, it was concluded that HSE had great potential to develop into feed additive of crabs, which could enhance the innate immunity of Chinese mitten crabs E. sinensis effectively after A. hydrophila infection. |
| 资助项目 | China Postdoctoral Science Foundation[2017M610427] ; Shandong Natural Science Foundation Project[ZR2016CP22] ; National Natural Science Foundation of China[31300545] ; National Natural Science Foundation of China[31700238] ; Key R & D project in Shandong[2017YYSP027] ; Shandong Province Higher Educational Science and Technology Program[J15LM11] ; Shandong Provincial Natural Science Foundation of China[ZR2017PC007] |
| WOS研究方向 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000447571600036 |
| 出版者 | ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/160482]  |
| 专题 | 中国科学院海洋研究所 |
| 通讯作者 | Wang, Zhen; Shi, Xiaowei |
| 作者单位 | 1.Linyi Univ, Coll Pharm, Linyi 276000, Shandong, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, Qingdao 266071, Peoples R China 3.Hainan Univ, Minist Educ, Key Lab Trop Biol Resources, Haikou 570228, Hainan, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhao, Zhilong,Zhang, Haijuan,Wang, Mengqiang,et al. The ethanol extract of honeysuckle stem modulates the innate immunity of Chinese mitten crab Eriocheir sinensis against Aeromonas hydrophila[J]. FISH & SHELLFISH IMMUNOLOGY,2018,82:304-311. |
| APA | Zhao, Zhilong.,Zhang, Haijuan.,Wang, Mengqiang.,Zhang, Chun.,Kuang, Pengqun.,...&Shi, Xiaowei.(2018).The ethanol extract of honeysuckle stem modulates the innate immunity of Chinese mitten crab Eriocheir sinensis against Aeromonas hydrophila.FISH & SHELLFISH IMMUNOLOGY,82,304-311. |
| MLA | Zhao, Zhilong,et al."The ethanol extract of honeysuckle stem modulates the innate immunity of Chinese mitten crab Eriocheir sinensis against Aeromonas hydrophila".FISH & SHELLFISH IMMUNOLOGY 82(2018):304-311. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。