The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect
文献类型：期刊论文
| 作者 | Jin, Qiu1,2,3 ; Yu, Huahua1,2; Li, Pengcheng1,2
|
| 刊名 | CURRENT MEDICINAL CHEMISTRY
 |
| 出版日期 | 2018 |
| 卷号 | 25期号:7页码:861-878 |
| 关键词 | Anti-obesity marine-derived digestive enzyme appetite fat absorption adipogenesis thermogenesis utilization |
| ISSN号 | 0929-8673 |
| DOI | 10.2174/0929867324666170602082620 |
| 通讯作者 | Yu, Huahua(yuhuahua@qdio.ac.cn) ; Li, Pengcheng(pcli@qdio.ac.cn) |
| 英文摘要 | Background: Obesity is a global epidemic throughout the world. There is thus increasing interest in searching for natural bioactive compounds with anti-obesity effect. A number of marine compounds have been regarded as potential sources of bioactive compounds and are associated with an anti-obesity effect. Objective: Marine-derived compounds with anti-obesity effect and their current applications, methods and indicators for the evaluation of anti-obesity activity are summarized in this review. in order to make contributions to the development of marine-derived functional food against obesity. Results: In this review, an overview of marine-derived compounds with anti-obesity effect, including marine polysaccharides, marine lipid, marine peptides, marine carotenoids is intensively made with an emphasis on their efficacy and mechanism of action. Meanwhile, methods and indicators for the evaluation of anti-obesity activity are discussed. We summarize these methods into three categories: in vitro assay (including adsorption experiments and enzyme inhibitory assay), cell line study, animal experiments and clinical experiments. In addition, a brief introduction of the current applications of marine bioactive compounds with anti-obesity activity is discussed. Conclusion: Marine environment is a rich source of both biological and chemical diversity. In the past decades, numerous novel compounds with anti-obesity activity have been obtained from marine organisms, and many of them have been applied to industrial production such as functional foods and pharmaceuticals. Further studies are needed to explore the above-mentioned facts. |
| 资助项目 | NSFC-Shandong Joint Fund[U1606403] ; major projects of independent, Shandong[2013CXB80203] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000427719500006 |
| 出版者 | BENTHAM SCIENCE PUBL LTD |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/158390]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Yu, Huahua; Li, Pengcheng |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, 7 Nanhai Rd,7 Qingdao,Nanhai Rd, Qingdao 266071, Shandong, Peoples R China 2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Drugs & Bioprod, 1 Wenhai Rd, Qingdao 266237, Peoples R China 3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jin, Qiu,Yu, Huahua,Li, Pengcheng. The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect[J]. CURRENT MEDICINAL CHEMISTRY,2018,25(7):861-878. |
| APA | Jin, Qiu,Yu, Huahua,&Li, Pengcheng.(2018).The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect.CURRENT MEDICINAL CHEMISTRY,25(7),861-878. |
| MLA | Jin, Qiu,et al."The Evaluation and Utilization of Marine-derived Bioactive Compounds with Anti-Obesity Effect".CURRENT MEDICINAL CHEMISTRY 25.7(2018):861-878. |
入库方式： OAI收割
来源：海洋研究所
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