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New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535

文献类型：期刊论文

作者Yang, Sui-Qun1,2,3; Li, Xiao-Ming1,2; Li, Xin1,2; Li, Hong-Lei1,2; Meng, Ling-Hong1,2; Wang, Bin-Gui1,2
刊名PHYTOCHEMISTRY LETTERS
出版日期2018-06-01
卷号25页码:191-195
关键词Coculture Aspergillus sydowii Penicillium citrinum Citrinin analogue Antimicrobial activity Influenza neuraminidase inhibitory activity
ISSN号1874-3900
DOI10.1016/j.phytol.2018.04.023
通讯作者Wang, Bin-Gui(wangbg@ms.qdio.ac.cn)
英文摘要Ten citrinin analogues (1-10), including a new citrinin dimer (seco-penicitrinol A, 2) and a new citrinin monomer (penicitrinol L, 3), were isolated from the EtOAc extracts of the coculture of two marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535. Their structures were elucidated by detailed analysis of their NMR spectra, ECDs, HRESIMS, optical rotation, and X-ray crystallographic data, and by comparison with literature data as well. The crystal structure of compound 1 was reported for the first time in this paper and resulted in unambiguous confirmation of its absolute configuration as 3R, 4S, 2'R, and 3'S, while the absolute configuration of compound 3 was determined by TDDFT calculations of its ECD spectrum. The antimicrobial and influenza neuraminidase inhibitory activities of compounds 1-10 were evaluated.
资助项目Natural Science Foundation of China (NSFC)[31330009] ; NSFC-Shandong Joint Fund for Marine Science Research Centers[U1606403] ; Taishan Scholar Project from Shandong Province of China
WOS研究方向Plant Sciences ; Pharmacology & Pharmacy
语种英语
WOS记录号WOS:000433356000039
出版者ELSEVIER SCIENCE BV
源URL[http://ir.qdio.ac.cn/handle/337002/159242]  
专题海洋研究所_实验海洋生物学重点实验室
通讯作者Wang, Bin-Gui
作者单位1.Chinese Acad Sci, Inst Oceanol, Key Lab Expt Marine Biol, Nanhai Rd 7, Qingdao 266071, Peoples R China
2.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Nanhai Rd 7, Qingdao 266071, Peoples R China
3.Univ Chinese Acad Sci, Yuquan Rd 19A, Beijing 100049, Peoples R China
推荐引用方式
GB/T 7714		 Yang, Sui-Qun,Li, Xiao-Ming,Li, Xin,et al. New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535[J]. PHYTOCHEMISTRY LETTERS,2018,25:191-195.
APA Yang, Sui-Qun,Li, Xiao-Ming,Li, Xin,Li, Hong-Lei,Meng, Ling-Hong,&Wang, Bin-Gui.(2018).New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535.PHYTOCHEMISTRY LETTERS,25,191-195.
MLA Yang, Sui-Qun,et al."New citrinin analogues produced by coculture of the marine algal-derived endophytic fungal strains Aspergillus sydowii EN-534 and Penicillium citrinum EN-535".PHYTOCHEMISTRY LETTERS 25(2018):191-195.

入库方式： OAI收割

来源：海洋研究所

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