Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China
文献类型：期刊论文
| 作者 | Peng, Quancai1,2,3,4 ; Song, Jinming1,2,3,4; Li, Xuegang1,2,3,4; Yuan, Huamao1,2,3,4; Yang, Guang1,2,3,4
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| 刊名 | APPLIED SCIENCES-BASEL
 |
| 出版日期 | 2019-03-02 |
| 卷号 | 9期号:6页码:17 |
| 关键词 | PhACs snow ecological risk Jiaozhou Bay (JZB) |
| DOI | 10.3390/app9061078 |
| 通讯作者 | Song, Jinming(jmsong@qdio.ac.cn) |
| 英文摘要 | The occurrence and distribution of 110 pharmaceutically active compounds (PhACs) were investigated in snow near Jiaozhou Bay (JZB), North China. All target substances were analyzed using solid phase extraction followed by liquid chromatography coupled to tandem mass spectrometry.A total of 38 compounds were detected for the first time in snow, including 23 antibiotics, eight hormones, three nonsteroidal anti-inflammatory drugs, two antipsychotics, one beta-adrenergic receptor and one hypoglycemic drug. The total concentration of PhACs in snow ranged from 52.80 ng/L to 1616.02 ng/L. The compounds found at the highest mean concentrations included tetracycline (125.81 ng/L), desacetylcefotaxime (17.73 ng/L), ronidazole (8.79 ng/L) and triamcinolone diacetate (2.84 ng/L). The contribution of PhACs in the vicinity of JZB to the PhACs in the snow is far greater than the contribution of those transmitted over a long distance. PhACs are mainly derived from drugs applied to local humans and animals. Based on the individual risk quotient (RQ) values, tetracycline poses high risks to the relevant aquatic organisms (algae and invertebrates). The rational application and scientific management of PhACs is an effective approach to reduce the ecological risks in JZB. |
| 资助项目 | Fund of the Key Science and Technology Innovation Program - Shandong Province ; Qingdao National Laboratory for Marine Science and Technology[2018SDKJ0504-1] ; National Natural Science Foundation of China[41676068] ; Development of Instrument & Equipment Function and Technical Innovation Project of CAS[HYQY-GNKF2016-1-2] |
| WOS研究方向 | Chemistry ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000465017200043 |
| 出版者 | MDPI |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/161255]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Song, Jinming |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Shandong, Peoples R China 2.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 3.Pilot Natl Lab Marine Sci & Technol Qingdao, Lab Marine Ecol & Environm Sci, Qingdao 266237, Shandong, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Shandong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Peng, Quancai,Song, Jinming,Li, Xuegang,et al. Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China[J]. APPLIED SCIENCES-BASEL,2019,9(6):17. |
| APA | Peng, Quancai,Song, Jinming,Li, Xuegang,Yuan, Huamao,&Yang, Guang.(2019).Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China.APPLIED SCIENCES-BASEL,9(6),17. |
| MLA | Peng, Quancai,et al."Characterization, Source and Risk of Pharmaceutically Active Compounds (PhACs) in the Snow Deposition Near Jiaozhou Bay, North China".APPLIED SCIENCES-BASEL 9.6(2019):17. |
入库方式： OAI收割
来源：海洋研究所
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