New insights into the aquatic photochemistry of fluoroquinolone antibiotics: Direct photodegradation, hydroxyl-radical oxidation, and antibacterial activity changes
文献类型：期刊论文
| 作者 | Ren, Honglei1; Ge, Linke1; Na, Guangshui1; Zhang, Siyu2; Li, Kai1; Zhang, Peng1; Yao, Ziwei1 |
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2015-09-15 |
| 卷号 | 527页码:12-17 |
| 关键词 | Fluoroquinolones Photolysis Oxidation Kinetics Transformation Products Antibacterial Activity |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2015.04.099 |
| 英文摘要 | The ubiquity and photoreactivity of fluoroquinolone antibiotics (FQs) in surface waters urge new insights into their aqueous photochemical behavior. This study concerns the photochemistry of 6 FQs: ciprofloxacin, danofloxacin, levofloxacin, sarafloxacin, difloxacin and enrofloxacin. Methods were developed to calculate their solar direct photodegradation half-lives (t(d,E)) and hydroxyl-radical oxidation half-lives (t(center dot OH,E)) in sunlit surface waters. The td, E values range from 0.56 min to 28.8 min at 45 degrees N latitude, whereas t(center dot OH,E) ranges from 3.24 h to 33.6 h, suggesting that most FQs tend to undergo fast direct photolysis rather than hydroxyl-radical oxidation in surface waters. However, a case study for levofloxacin and sarafloxacin indicated that the hydroxyl-radical oxidation induced risky photochlorination and resulted inmulti-degradation pathways, such as piperazinyl hydroxylation and clearage. Changes in the antibacterial activity of FQs caused by photodegradation in various waters were further examined using Escherichia coli, and it was found that the activity evolution depended on primary photodegradation pathways and products. Primary intermediates with intact FQ nuclei retained significant antibacterial activity. These results are important for assessing the fate and risk of FQs in surface waters. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000356225300002 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://210.72.129.5/handle/321005/122085]  |
| 专题 | 中国科学院沈阳应用生态研究所 |
| 通讯作者 | Zhang, Peng |
| 作者单位 | 1.Natl Marine Environm Monitoring Ctr, Key Lab Ecol Environm Coastal Areas SOA, Dalian 116023, Peoples R China 2.Chinese Acad Sci, Inst Appl Ecol, Shenyang 110016, Peoples R China |
| 推荐引用方式 GB/T 7714 | Ren, Honglei,Ge, Linke,Na, Guangshui,et al. New insights into the aquatic photochemistry of fluoroquinolone antibiotics: Direct photodegradation, hydroxyl-radical oxidation, and antibacterial activity changes[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2015,527:12-17. |
| APA | Ren, Honglei.,Ge, Linke.,Na, Guangshui.,Zhang, Siyu.,Li, Kai.,...&Yao, Ziwei.(2015).New insights into the aquatic photochemistry of fluoroquinolone antibiotics: Direct photodegradation, hydroxyl-radical oxidation, and antibacterial activity changes.SCIENCE OF THE TOTAL ENVIRONMENT,527,12-17. |
| MLA | Ren, Honglei,et al."New insights into the aquatic photochemistry of fluoroquinolone antibiotics: Direct photodegradation, hydroxyl-radical oxidation, and antibacterial activity changes".SCIENCE OF THE TOTAL ENVIRONMENT 527(2015):12-17. |
入库方式： OAI收割
来源：沈阳应用生态研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。