Biological toxicity of cellulose nanocrystals (CNCs) against the luxCDABE-based bioluminescent bioreporter Escherichia coli 652T7
文献类型：期刊论文
| 作者 | Du, Liyu1,2; Arnholt, Kelly2; Ripp, Steven2; Sayler, Gary2; Wang, Siqun3; Liang, Chenghua1; Wang, Jingkuan1; Zhuang, Jie2,4 |
| 刊名 | ECOTOXICOLOGY
 |
| 出版日期 | 2015-12-01 |
| 卷号 | 24期号:10页码:2049-2053 |
| 关键词 | Cellulose Nanocrystals Toxicity Lux Bioreporter Bioluminescence |
| ISSN号 | 0963-9292 |
| DOI | 10.1007/s10646-015-1555-0 |
| 英文摘要 | The aim of this study was to evaluate the biological toxicity of cellulose nanocrystals (CNCs) using the constitutively bioluminescent luxCDABE-based bioreporter Escherichia coli 652T7. The effects of CNCs on E. c oli 652T7 biotoxicity were investigated at different CNC concentrations, reaction times, and IC50 values. CNC toxicity was also compared with and without ultrasonic dispersion to establish dispersibility effects. The results demonstrated that CNCs were not significantly toxic at concentrations at or below 250 mg/L. At concentrations higher than 300 mg/L, toxicity increased linearly as CNC concentrations increased up to 2000 mg/L. IC50 calculations demonstrated an increase in cytotoxicity as CNC exposure times increased, and elevated dispersibility of the CNCs were shown to increase cytotoxicity effects. These results suggest that CNCs can impact microbial populations if elevated concentration thresholds are met. |
| WOS研究方向 | Environmental Sciences & Ecology ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000365758200002 |
| 出版者 | SPRINGER |
| 源URL | [http://210.72.129.5/handle/321005/122305]  |
| 专题 | 中国科学院沈阳应用生态研究所 |
| 通讯作者 | Zhuang, Jie |
| 作者单位 | 1.Shenyang Agr Univ, Coll Land & Environm, Shenyang 110866, Peoples R China 2.Univ Tennessee, Ctr Environm Biotechnol, Knoxville, TN 37996 USA 3.Univ Tennessee, Ctr Renewable Carbon, Knoxville, TN 37996 USA 4.Chinese Acad Sci, Key Lab Pollut Ecol & Environm Engn, Shenyang 110016, Peoples R China |
| 推荐引用方式 GB/T 7714 | Du, Liyu,Arnholt, Kelly,Ripp, Steven,et al. Biological toxicity of cellulose nanocrystals (CNCs) against the luxCDABE-based bioluminescent bioreporter Escherichia coli 652T7[J]. ECOTOXICOLOGY,2015,24(10):2049-2053. |
| APA | Du, Liyu.,Arnholt, Kelly.,Ripp, Steven.,Sayler, Gary.,Wang, Siqun.,...&Zhuang, Jie.(2015).Biological toxicity of cellulose nanocrystals (CNCs) against the luxCDABE-based bioluminescent bioreporter Escherichia coli 652T7.ECOTOXICOLOGY,24(10),2049-2053. |
| MLA | Du, Liyu,et al."Biological toxicity of cellulose nanocrystals (CNCs) against the luxCDABE-based bioluminescent bioreporter Escherichia coli 652T7".ECOTOXICOLOGY 24.10(2015):2049-2053. |
入库方式： OAI收割
来源：沈阳应用生态研究所
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