The chronic effects of lignin-derived bisphenol and bisphenol A in Japanese medaka Oryzias latipes
文献类型：期刊论文
| 作者 | Xie, Lingtian1; Li, Dan1; Chen, Qin2; Cao, Jinling3; Chen, Hongxing1; Li, Lixia1; Cedergreen, Nina4; Xie, Haibo5 |
| 刊名 | AQUATIC TOXICOLOGY
 |
| 出版日期 | 2016 |
| 卷号 | 170页码:199-207 |
| 关键词 | Bisphenol a Lignin-derived Bisphenol (Ld-bp) Japanese Medaka Vitellogenin Histopathology Reproduction |
| ISSN号 | 0166-445X |
| DOI | 10.1016/j.aquatox.2015.11.024 |
| 英文摘要 | One of the ultimate goals of green chemistry is to produce greener and more environmentally friendly chemicals to replace the existing toxic chemicals. In this study, Japanese medaka were exposed to 1.5 mg/L of bisphenol A or lignin-derived bisphenol for 60 days, and the expressions of various biochemical markers, effects on reproduction, and histopathology were evaluated. The results showed that concentrations of liver vitellogenin of LD-BP exposed males were approximately 125% higher compared to the control males. Total number of eggs from the BPA and LD-BP exposed fish was approximately 47% (p < 0.001) and 25% (p < 0.05) less than the control fish, respectively. Total number of brood was lower from the BPA (46%, p <0.05) and LD-BP (17%,p<0.05) exposed fish than that of the control fish. Relative to the control fish, catalase and glutathione-S-transferase were significantly affected by the two chemicals in all tested tissues. BPA and LD-BP caused lipid peroxidation in all the tested tissues. Furthermore, acetylcholinesterase and alpha-glucosidase activity were significantly inhibited. Histopathological analysis showed that both the testis and ovary were mildly damaged by both chemicals. LD-BP affected medaka slightly more severe than BPA except on the reproduction, which was most likely due to different uptake, translocation, binding to targets and metabolism. Our results demonstrated that chronic exposure to both chemicals caused several adverse effects to medaka. Further research on the toxicity of LD-BP to other aquatic organisms is needed before substitution of traditional BPA with LD-BP can be recommended. (C) 2015 Elsevier B.V. All rights reserved. |
| WOS研究方向 | Marine & Freshwater Biology ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:000368564500020 |
| 出版者 | ELSEVIER SCIENCE BV |
| 源URL | [http://210.72.129.5/handle/321005/122415]  |
| 专题 | 中国科学院沈阳应用生态研究所 |
| 通讯作者 | Xie, Lingtian |
| 作者单位 | 1.Chinese Acad Sci, Inst Appl Ecol, Key Lab Pollut Ecol & Environm Engn, Shenyang 110016, Peoples R China 2.Chinese Acad Sci, Dalian Inst Chem Phys, Dalian Natl Lab Clean Energy, Dalian 116023, Peoples R China 3.Shanxi Agr Univ, State Key Lab Ecol Anim Husb & Environm Vet Med, Taigu 030801, Peoples R China 4.Univ Copenhagen, Sect Environm Chem & Phys, Dept Plant & Environm Sci, DK-1871 Copenhagen, Denmark 5.Guizhou Univ, Coll Mat & Met, Dept Polymer Mat & Engn, Beijing 550025, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xie, Lingtian,Li, Dan,Chen, Qin,et al. The chronic effects of lignin-derived bisphenol and bisphenol A in Japanese medaka Oryzias latipes[J]. AQUATIC TOXICOLOGY,2016,170:199-207. |
| APA | Xie, Lingtian.,Li, Dan.,Chen, Qin.,Cao, Jinling.,Chen, Hongxing.,...&Xie, Haibo.(2016).The chronic effects of lignin-derived bisphenol and bisphenol A in Japanese medaka Oryzias latipes.AQUATIC TOXICOLOGY,170,199-207. |
| MLA | Xie, Lingtian,et al."The chronic effects of lignin-derived bisphenol and bisphenol A in Japanese medaka Oryzias latipes".AQUATIC TOXICOLOGY 170(2016):199-207. |
入库方式： OAI收割
来源：沈阳应用生态研究所
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