Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes
文献类型：期刊论文
| 作者 | Jiang, Yong2; Li, Hui2; Li, Xiaobin1,2; Wang, Yafei2; Brown, Celeste J.3; Yao, Fei1,2; Top, Eva M.3 |
| 刊名 | FEMS MICROBIOLOGY ECOLOGY
 |
| 出版日期 | 2016 |
| 卷号 | 92期号:1 |
| 关键词 | Incp-1 Epsilon Plasmid Comparative Genome Analysis Antibiotic Resistance Horizontal Gene Transfer Petroleum Polluted Soil Wastewater |
| ISSN号 | 0168-6496 |
| DOI | 10.1093/femsec/fiv151 |
| 英文摘要 | The IncP-1 epsilon subgroup is a recently identified phylogenetic clade within IncP-1 plasmids, which plays an important role in the spread of antibiotic resistance and degradation of xenobiotic pollutants. Here, four IncP-1 epsilon plasmids were exogenously captured from a petroleum-contaminated habitat in China and compared phylogenetically and genomically with previously reported IncP-1 epsilon and other IncP-1 plasmids. The IncP-1 epsilon plasmids can be clearly subdivided into two subclades, designated as epsilon-I and epsilon-II, based on phylogenetic analysis of backbone proteins TraI and TrfA. This was further supported by comparison of concatenated backbone genes. Moreover, the two subclades differed in the transposon types, phenotypes and insertion locations of the accessory elements. The accessory genes on epsilon-I plasmids were inserted between parA and traC, and harbored ISPa17 and Tn402-like transposon modules, typically carrying antibiotic resistance genes. In contrast, the accessory elements on epsilon-II plasmids were typically located between trfA and oriV, and contained IS1071, which was commonly inserted within the Tn501-like transposon, typically harboring a cluster of genes encoding mercury resistance and/or catabolic pathways. Our study is one of the first to compare IncP-1 plasmid genomes from China, expands the available collection of IncP-1 epsilon plasmids and enhances our understanding of their diversity, biogeography and evolutionary history. |
| WOS研究方向 | Microbiology |
| 语种 | 英语 |
| WOS记录号 | WOS:000371249300008 |
| 出版者 | OXFORD UNIV PRESS |
| 源URL | [http://210.72.129.5/handle/321005/122501]  |
| 专题 | 中国科学院沈阳应用生态研究所 |
| 通讯作者 | Li, Hui |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Inst Appl Ecol, State Key Lab Forest & Soil Ecol, Wenhua Rd 72, Shenyang 110164, Peoples R China 3.Univ Idaho, Inst Bioinformat & Evolutionary Studies IBEST, Dept Biol Sci, Moscow, ID 83844 USA |
| 推荐引用方式 GB/T 7714 | Jiang, Yong,Li, Hui,Li, Xiaobin,et al. Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes[J]. FEMS MICROBIOLOGY ECOLOGY,2016,92(1). |
| APA | Jiang, Yong.,Li, Hui.,Li, Xiaobin.,Wang, Yafei.,Brown, Celeste J..,...&Top, Eva M..(2016).Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes.FEMS MICROBIOLOGY ECOLOGY,92(1). |
| MLA | Jiang, Yong,et al."Diversification of broad host range plasmids correlates with the presence of antibiotic resistance genes".FEMS MICROBIOLOGY ECOLOGY 92.1(2016). |
入库方式： OAI收割
来源：沈阳应用生态研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。