A pressure-driven gas-diffusion/permeation micropump for self-activated sample transport in an extreme micro-environment
文献类型：期刊论文
| 作者 | Wu, Wenming |
| 刊名 | ANALYST
 |
| 出版日期 | 2018-10-21 |
| 卷号 | 143期号:20页码:4819-4835 |
| ISSN号 | 0003-2654 |
| DOI | 10.1039/c8an01120f |
| 通讯作者 | Wu, Wenming(wuwm@ciomp.ac.cn) |
| 英文摘要 | The micropump is the most important functional unit of a micro total analysis system (TAS). An ideal microfluidics system should adopt simple, stable, robust, inexpensive, and integrated on-chip strategies to transport samples for downstream applications, with little or no external energy consumption and limited manual intervention. Nevertheless, it remains a key challenge for traditional micropumps to be directly integrated into self-contained and disposable TAS for velocity-stable and passive sample transport. The best way to assess the capability of passive micropumps is to evaluate their pumping performance in extreme environments, e.g. a 3D configurated microchannel instead of a 2D configuration, high temperature conditions instead of at room temperature, a long microchannel instead of short microchannel, a complex topological microsystem (e.g. a microvascular network interconnecting multiple inlets and outlets) instead of a simple topological microsystem (e.g. a one-directional microchannel connecting only one inlet and one outlet), and multi-phase microdroplet transport instead of single-phase plug transport. In this review, a novel micropumping methodology - a pressure-driven gas-diffusion/permeation micropump - is described, which is the first review paper dedicated to this subject. A comprehensive overview is provided for comparison between this novel micropumping methodology and traditional passive micropumps, especially for applications in stable velocity control in the aforementioned extreme environments. Compared with mainstream conventional micropumps, we confirm that pressure-driven gas-diffusion/permeation micropumps combine a number of superior properties all into one device, such as small size, simple structure, without the need for microfabrication procedures or external power consumption, strong transport capacity, homogeneous flow velocity, delivery capacity for both multi-phase microdroplets and single-phase plugs, long-distance transport, persistent pumping for both 3D microchannels and complex topological microsystems (e.g. a biomimetic microvasculature), low cost, ease of microdevice integration, bubble suppression and amazing stability at high temperatures. An advanced outlook and perspectives for the future development of this novel micropump are also discussed, which may serve as a starting point for researchers in the microfluidics fields to harness pressure-driven gas-diffusion/permeation micropumps for downstream applications. |
| WOS关键词 | POLYMERASE-CHAIN-REACTION ; MICROFLUIDIC DEVICES ; CAPILLARY-DRIVEN ; SINGLE HEATER ; DIGITAL PCR ; POLYDIMETHYLSILOXANE PDMS ; PIEZOELECTRIC MICROPUMP ; DROPLET GENERATION ; CELL-CULTURE ; FLOW |
| 资助项目 | CAS Pioneer Hundred Talents Program ; National Natural Science Foundation of China[61704169] ; Natural Science Foundation of Jilin Province[20180520112JH] ; talent project of Jilin Province |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| 出版者 | ROYAL SOC CHEMISTRY |
| WOS记录号 | WOS:000448338200002 |
| 资助机构 | CAS Pioneer Hundred Talents Program ; National Natural Science Foundation of China ; Natural Science Foundation of Jilin Province ; talent project of Jilin Province |
| 源URL | [http://ir.ciomp.ac.cn/handle/181722/60487]  |
| 专题 | 中国科学院长春光学精密机械与物理研究所 |
| 通讯作者 | Wu, Wenming |
| 作者单位 | Chinese Acad Sci, Changchun Inst Opt Fine Mech & Phys, State Key Lab Appl Opt, Changchun 130033, Jilin, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Wenming. A pressure-driven gas-diffusion/permeation micropump for self-activated sample transport in an extreme micro-environment[J]. ANALYST,2018,143(20):4819-4835. |
| APA | Wu, Wenming.(2018).A pressure-driven gas-diffusion/permeation micropump for self-activated sample transport in an extreme micro-environment.ANALYST,143(20),4819-4835. |
| MLA | Wu, Wenming."A pressure-driven gas-diffusion/permeation micropump for self-activated sample transport in an extreme micro-environment".ANALYST 143.20(2018):4819-4835. |
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