中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Imitation of nature: Bionic design in the study of particle adjuvants

文献类型:期刊论文

作者Wu, Jie1,2; Ma, Guanghui1,2,3
刊名JOURNAL OF CONTROLLED RELEASE
出版日期2019-06-10
卷号303页码:101-108
ISSN号0168-3659
关键词Bionic design Vaccine Adjuvant Nano/micro-particle Pathogen
DOI10.1016/j.jconrel.2019.04.004
英文摘要Vaccine adjuvants play an increasingly important role in the development of modern vaccines. Among of them, particle adjuvants have received wide attention due to their unique properties. In order to develop effective particle adjuvants, mimicking natural pathogens is one of the important strategies. By adopting different materials, preparation methods and design ideas, the researchers obtained various particle adjuvants that mimic the shape, surface properties and action mechanisms of natural pathogens. This mini-review outlines some selected relevant recent literatures, discusses several bionic design strategies of particle adjuvants and some important barriers to further study are described.
WOS关键词DELIVERY-SYSTEM ; BACTERIAL GHOSTS ; VACCINE DELIVERY ; IMMUNE-RESPONSE ; DENDRITIC CELLS ; NANOPARTICLES ; ANTIGEN ; MICROPARTICLES ; SIZE ; ACTIVATION
资助项目National Natural Science Foundation of China (NSFC)[21576268] ; National Natural Science Foundation of China (NSFC)[21776287] ; National Natural Science Foundation of China (NSFC)[21821005] ; Key Research Program of the Chinese Academy of Sciences[KFZD-SW-218] ; International Cooperation Project of the Chinese Academy of Sciences[122111KYSB20180021]
WOS研究方向Chemistry ; Pharmacology & Pharmacy
语种英语
出版者ELSEVIER SCIENCE BV
WOS记录号WOS:000471239600010
资助机构National Natural Science Foundation of China (NSFC) ; Key Research Program of the Chinese Academy of Sciences ; International Cooperation Project of the Chinese Academy of Sciences
源URL[http://ir.ipe.ac.cn/handle/122111/30054]  
专题中国科学院过程工程研究所
通讯作者Ma, Guanghui
作者单位1.Chinese Acad Sci, Inst Proc Engn, State Key Lab Biochem Engn, Beijing 100190, Peoples R China
2.Chinese Acad Sci, Inst Proc Engn, PLA Key Lab Biopharmaceut Prod & Formulat Engn, Beijing 100190, Peoples R China
3.Jiangsu Natl Synerget Innovat Ctr Adv Mat, Nanjing 211816, Jiangsu, Peoples R China
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GB/T 7714
Wu, Jie,Ma, Guanghui. Imitation of nature: Bionic design in the study of particle adjuvants[J]. JOURNAL OF CONTROLLED RELEASE,2019,303:101-108.
APA Wu, Jie,&Ma, Guanghui.(2019).Imitation of nature: Bionic design in the study of particle adjuvants.JOURNAL OF CONTROLLED RELEASE,303,101-108.
MLA Wu, Jie,et al."Imitation of nature: Bionic design in the study of particle adjuvants".JOURNAL OF CONTROLLED RELEASE 303(2019):101-108.

入库方式: OAI收割

来源:过程工程研究所

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