Graphene quantum dots functionalized beta-cyclodextrin and cellulose chiral stationary phases with enhanced enantioseparation performance
文献类型：期刊论文
| 作者 | Wu, Qi1,2,3; Gao, Jie1,2,3; Chen, Lixiao1,2,3; Dong, Shuqing1,2; Li, Hui1,2; Qiu, Hongdeng1,2; Zhao, Liang1,2 |
| 刊名 | Journal of chromatography a
 |
| 出版日期 | 2019-08-30 |
| 卷号 | 1600页码:209-218 |
| ISSN号 | 0021-9673 |
| 关键词 | Graphene quantum dots Cyclodextrin Cellulose Molecular modeling Enantioseparation |
| DOI | 10.1016/j.chroma.2019.04.053 |
| 通讯作者 | Qiu, hongdeng(hdqiu@licp.cas.cn) ; Zhao, liang(zhaol@licp.cas.cn) |
| 英文摘要 | Graphene quantum dots (gqd) functionalized beta-cyclodextrin (beta-cd) and cellulose silica composites were first prepared and applied in hplc as chiral stationary phases (csp) to investigate the effect of gqds on chiral separation. through comparing the enantioseparation performance of gqds functionalized beta-cd or cellulose csps and unmodified beta-cd or cellulose csps, we found gqds enhanced the enantioseparation performance of nature beta-cd, beta-cd-3,5-dimethylphenylcarbamate derivative and cellulose-3,5-dimethylphenylcarbamate derivative. molecular modeling was applied to understand and theoretically study the enhancement mechanism of gqds for enantioseparation. according to molecular simulation results, gqds provide extra interactions such as hydrophobic, hydrogen bond and pi-pi interaction when chiral selector interacts with enantiomers, which enhances the chiral recognition ability indirectly. the molecular simulation results showed a good agreement with the experimental results. our work reveals the enhancement performance of gqds for chiral separation, it can be expected that gqds-based chiral composites and chiral gqds have great prospect in chiral separation and other research fields such as asymmetric synthesis, chiral catalysis, chiral recognition and drug delivery. (c) 2019 elsevier b.v. all rights reserved. |
| 收录类别 | SCI |
| WOS关键词 | OXIDE-MAGNETIC NANOCOMPOSITES ; CAPILLARY-ELECTROPHORESIS ; BONDED SILICA ; SEPARATION ; HPLC ; FLUORESCENCE ; RESOLUTION ; MECHANISM ; AMYLOSE ; ACID |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| WOS类目 | Biochemical Research Methods ; Chemistry, Analytical |
| 语种 | 英语 |
| 出版者 | ELSEVIER SCIENCE BV |
| WOS记录号 | WOS:000472687800024 |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2555402 |
| 专题 | 寒区旱区环境与工程研究所 |
| 通讯作者 | Qiu, Hongdeng; Zhao, Liang |
| 作者单位 | 1.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Chem Northwestern Plant Resources, Lanzhou, Gansu, Peoples R China 2.Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou, Gansu, Peoples R China 3.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Qi,Gao, Jie,Chen, Lixiao,et al. Graphene quantum dots functionalized beta-cyclodextrin and cellulose chiral stationary phases with enhanced enantioseparation performance[J]. Journal of chromatography a,2019,1600:209-218. |
| APA | Wu, Qi.,Gao, Jie.,Chen, Lixiao.,Dong, Shuqing.,Li, Hui.,...&Zhao, Liang.(2019).Graphene quantum dots functionalized beta-cyclodextrin and cellulose chiral stationary phases with enhanced enantioseparation performance.Journal of chromatography a,1600,209-218. |
| MLA | Wu, Qi,et al."Graphene quantum dots functionalized beta-cyclodextrin and cellulose chiral stationary phases with enhanced enantioseparation performance".Journal of chromatography a 1600(2019):209-218. |
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来源：寒区旱区环境与工程研究所
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