The effect of gamma-Fe2O3 nanoparticles on Escherichia coli genome
文献类型：期刊论文
| 作者 | He, Shiying1; Feng, Youzhi2; Gu, Ning1; Zhang, Yu1; Lin, Xiangui2 |
| 刊名 | ENVIRONMENTAL POLLUTION
 |
| 出版日期 | 2011-12-01 |
| 卷号 | 159期号:12页码:3468-3473 |
| 关键词 | Mutations Escherichia coli gamma-Fe2O3 nanoparticles |
| ISSN号 | 0269-7491 |
| DOI | 10.1016/j.envpol.2011.08.024 |
| 通讯作者 | Gu, Ning(guning@seu.edu.cn) |
| 英文摘要 | Extensive production and application of gamma-Fe2O3 magnetic nanoparticles (MNPs) has increased their potential risk on environment and human health. This report illustrates a genetic impact of gamma-Fe2O3 magnetic nanoparticles (MNPs) on Escherichia colt (E. coli). After 3000-generation incubation with MNPs addition, obvious genomic variations were revealed by using repetitive extragenic palindromic PCR (rep-PCR) DNA fingerprint technique. The physicochemical interactions between MNPs and bacteria could be responsible for such genomic responses. It was revealed that Fe3+ concentration increased in the medium. Transmission electronic microscopy (TEM) and flow cytometry (FCM) analysis consistently demonstrated the occurrences of adsorption and membranes-internalization of MNPs outside and inside cells. Both increased Fe3+ ion and the uptake of MNPs facilitated Fe binding with proteins and DNA strands, resulting in enhancing the mutation frequency of E. colt. Our results would be of great help to assessing the potential impact of MNPs on human and environment. (C) 2011 Elsevier Ltd. All rights reserved. |
| 收录类别 | SCI |
| WOS关键词 | SUPERPARAMAGNETIC IRON-OXIDE ; MAGNETIC NANOPARTICLES ; TITANIUM-DIOXIDE ; TOXICITY ; BACTERIA ; AGENTS ; DIVERSITY ; GROWTH ; CELLS ; TIO2 |
| WOS研究方向 | Environmental Sciences & Ecology |
| WOS类目 | Environmental Sciences |
| 语种 | 英语 |
| WOS记录号 | WOS:000296397300026 |
| 出版者 | ELSEVIER SCI LTD |
| URI标识 | http://www.irgrid.ac.cn/handle/1471x/2559053 |
| 专题 | 南京土壤研究所 |
| 通讯作者 | Gu, Ning |
| 作者单位 | 1.Southeast Univ, Sch Biol Sci & Med Engn, Jiangsu Lab Biomat & Devices, Nanjing 210096, Peoples R China 2.Chinese Acad Sci, Inst Soil Sci, State Key Lab Soil & Sustainable Agr, Nanjing 210008, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Shiying,Feng, Youzhi,Gu, Ning,et al. The effect of gamma-Fe2O3 nanoparticles on Escherichia coli genome[J]. ENVIRONMENTAL POLLUTION,2011,159(12):3468-3473. |
| APA | He, Shiying,Feng, Youzhi,Gu, Ning,Zhang, Yu,&Lin, Xiangui.(2011).The effect of gamma-Fe2O3 nanoparticles on Escherichia coli genome.ENVIRONMENTAL POLLUTION,159(12),3468-3473. |
| MLA | He, Shiying,et al."The effect of gamma-Fe2O3 nanoparticles on Escherichia coli genome".ENVIRONMENTAL POLLUTION 159.12(2011):3468-3473. |
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来源：南京土壤研究所
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