中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum

文献类型:期刊论文

作者Su, Lei1,2; Yang, Liang1,3; Sun, Qin1,2; Zhao, Tingting1; Liu, Bianhua1,3; Jiang, Changlong1,3; Zhang, Zhongping1,4
刊名NEW JOURNAL OF CHEMISTRY
出版日期2018-05-07
卷号42期号:9页码:6867-6872
ISSN号1144-0546
DOI10.1039/c8nj00502h
英文摘要

Fluorescent paper sensors are widely used in the assays of environment, food and medicine; however, their applications usually have been limited due to the narrow color-change range and insensitivity of the color variation to dosage of target analytes. In this paper, we report a ratiometric fluorescent probe-based paper sensor regulated by the optimum proportion of gold nanoclusters stabilized by bovine serum albumin and fluorescent graphene oxide to achieve the maximum consecutive color change for visual determination of glucose in human serum. The oxidation of hydrogen peroxide produced by glucose quenches the red fluorescence emission of gold nanoclusters and unveils a consecutive color change from pink to blue with the corresponding dosage of glucose. This colorimetric paper sensor printed with the probe ink exhibits a dosage-sensitive allochromatic capability for the blood glucose concentration of 4-10 mM in human serum (normal concentration: 4.4-6.6 mM). The method reported here can open a window in predicting diseases related to abnormal glucose levels.

WOS关键词GOLD NANOCLUSTERS ; GRAPHENE OXIDE ; SENSITIVE DETERMINATION ; IONS ; TRINITROTOLUENE ; VISUALIZATION ; PROBE ; DOTS
资助项目National Basic Research Program of China[2015CB932002] ; China-Singapore Joint Project[2015DFG92510] ; Science and National Natural Science Foundation of China[21605144] ; Science and National Natural Science Foundation of China[21507134] ; Science and National Natural Science Foundation of China[21371174] ; Science and National Natural Science Foundation of China[21375131] ; Natural Science Foundation of Anhui Province[1408085QB29]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000431819200040
出版者ROYAL SOC CHEMISTRY
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/37140]  
专题合肥物质科学研究院_中科院合肥智能机械研究所
通讯作者Yang, Liang; Jiang, Changlong
作者单位1.Chinese Acad Sci, Inst Intelligent Machines, CAS Ctr Excellence Nanosci, Hefei 230031, Anhui, Peoples R China
2.Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China
3.Chinese Acad Sci, State Key Lab Transducer Technol, Hefei 230031, Anhui, Peoples R China
4.Anhui Univ, Sch Chem & Chem Engn, Hefei 230601, Anhui, Peoples R China
推荐引用方式
GB/T 7714
Su, Lei,Yang, Liang,Sun, Qin,et al. A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum[J]. NEW JOURNAL OF CHEMISTRY,2018,42(9):6867-6872.
APA Su, Lei.,Yang, Liang.,Sun, Qin.,Zhao, Tingting.,Liu, Bianhua.,...&Zhang, Zhongping.(2018).A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum.NEW JOURNAL OF CHEMISTRY,42(9),6867-6872.
MLA Su, Lei,et al."A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum".NEW JOURNAL OF CHEMISTRY 42.9(2018):6867-6872.

入库方式: OAI收割

来源:合肥物质科学研究院

浏览0
下载0
收藏0
其他版本

除非特别说明,本系统中所有内容都受版权保护,并保留所有权利。