A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum
文献类型:期刊论文
作者 | Su, Lei1,2; Yang, Liang1,3; Sun, Qin1,2; Zhao, Tingting1; Liu, Bianhua1,3; Jiang, Changlong1,3![]() ![]() |
刊名 | NEW JOURNAL OF CHEMISTRY
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出版日期 | 2018-05-07 |
卷号 | 42期号:9页码:6867-6872 |
ISSN号 | 1144-0546 |
DOI | 10.1039/c8nj00502h |
英文摘要 | Fluorescent paper sensors are widely used in the assays of environment, food and medicine; however, their applications usually have been limited due to the narrow color-change range and insensitivity of the color variation to dosage of target analytes. In this paper, we report a ratiometric fluorescent probe-based paper sensor regulated by the optimum proportion of gold nanoclusters stabilized by bovine serum albumin and fluorescent graphene oxide to achieve the maximum consecutive color change for visual determination of glucose in human serum. The oxidation of hydrogen peroxide produced by glucose quenches the red fluorescence emission of gold nanoclusters and unveils a consecutive color change from pink to blue with the corresponding dosage of glucose. This colorimetric paper sensor printed with the probe ink exhibits a dosage-sensitive allochromatic capability for the blood glucose concentration of 4-10 mM in human serum (normal concentration: 4.4-6.6 mM). The method reported here can open a window in predicting diseases related to abnormal glucose levels. |
WOS关键词 | GOLD NANOCLUSTERS ; GRAPHENE OXIDE ; SENSITIVE DETERMINATION ; IONS ; TRINITROTOLUENE ; VISUALIZATION ; PROBE ; DOTS |
资助项目 | National Basic Research Program of China[2015CB932002] ; China-Singapore Joint Project[2015DFG92510] ; Science and National Natural Science Foundation of China[21605144] ; Science and National Natural Science Foundation of China[21507134] ; Science and National Natural Science Foundation of China[21371174] ; Science and National Natural Science Foundation of China[21375131] ; Natural Science Foundation of Anhui Province[1408085QB29] |
WOS研究方向 | Chemistry |
语种 | 英语 |
WOS记录号 | WOS:000431819200040 |
出版者 | ROYAL SOC CHEMISTRY |
源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/37140] ![]() |
专题 | 合肥物质科学研究院_中科院合肥智能机械研究所 |
通讯作者 | Yang, Liang; Jiang, Changlong |
作者单位 | 1.Chinese Acad Sci, Inst Intelligent Machines, CAS Ctr Excellence Nanosci, Hefei 230031, Anhui, Peoples R China 2.Univ Sci & Technol China, Dept Chem, Hefei 230026, Anhui, Peoples R China 3.Chinese Acad Sci, State Key Lab Transducer Technol, Hefei 230031, Anhui, Peoples R China 4.Anhui Univ, Sch Chem & Chem Engn, Hefei 230601, Anhui, Peoples R China |
推荐引用方式 GB/T 7714 | Su, Lei,Yang, Liang,Sun, Qin,et al. A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum[J]. NEW JOURNAL OF CHEMISTRY,2018,42(9):6867-6872. |
APA | Su, Lei.,Yang, Liang.,Sun, Qin.,Zhao, Tingting.,Liu, Bianhua.,...&Zhang, Zhongping.(2018).A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum.NEW JOURNAL OF CHEMISTRY,42(9),6867-6872. |
MLA | Su, Lei,et al."A ratiometric fluorescent paper sensor for consecutive color change-based visual determination of blood glucose in serum".NEW JOURNAL OF CHEMISTRY 42.9(2018):6867-6872. |
入库方式: OAI收割
来源:合肥物质科学研究院
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