Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008
文献类型：期刊论文
| 作者 | Qi, Shu-Hua; Liang, Xiao; Huang, Zhong-Hui; Ma, Xuan |
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2018 |
| 卷号 | 16期号:11页码:448 |
| 关键词 | deep-sea-derived fungus Cladosporium sphaerospermum tetramic acid cladosporiumins I-O |
| ISSN号 | 1660-3397 |
| 英文摘要 | Seven new unstable tetramic acid derivatives, cladosporiumins I-O (1-7), together with the known analogue cladodionen (8) were isolated from the extract of the deep-sea-derived fungus Cladosporium sphaerospermum EIODSF 008. Their structures were elucidated by spectroscopic analysis, quantum chemical calculations and ECD spectra. Compound 4 was a Mg complex of tetramic acid derivative. In acidic solvent, 4 could change to 1 and 6, and 7 could change to 5. In addition, 1, 5 and 8 existed as two exchangeable isomers, respectively. The structures of cladosporiumins E-H were reassigned as their Na complexes. The antibacterial and cytotoxic activities of 1-8 were also evaluated. However, because of their instability, all of the isolated compounds did not show significant antibacterial activity as the preliminary EtOAc extracts of the fungal strain. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17612]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.[Liang, Xiao 2.[Liang, Xiao 3.Huang, Zhong-Hui 4.Ma, Xuan 5.Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China 6.Univ Chinese Acad Sci, Beijing 100049, Peoples R China |
| 推荐引用方式 GB/T 7714 | Qi, Shu-Hua,Liang, Xiao,Huang, Zhong-Hui,et al. Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008[J]. MARINE DRUGS,2018,16(11):448. |
| APA | Qi, Shu-Hua,Liang, Xiao,Huang, Zhong-Hui,&Ma, Xuan.(2018).Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008.MARINE DRUGS,16(11),448. |
| MLA | Qi, Shu-Hua,et al."Unstable Tetramic Acid Derivatives from the Deep-Sea-Derived Fungus Cladosporium sphaerospermum EIODSF 008".MARINE DRUGS 16.11(2018):448. |
入库方式： OAI收割
来源：南海海洋研究所
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