中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Regulation of IL-17 by lncRNA of IRF-2 in the pearl oyster

文献类型:期刊论文

作者Zhang, Hua; Huang, Xian-De; Dai, Jia-ge; Lin, Ke-tao; Liu, Mei; Ruan, Hui-ting; Liu, Wen-guang; He, Mao-Xian; Zhao, Mi3
刊名FISH & SHELLFISH IMMUNOLOGY
出版日期2018
卷号81页码:108
关键词Pearl oyster lncIRF-2 PfIL-17 RNA interference Nucleus grafting
ISSN号1050-4648
英文摘要Long noncoding RNAs (lncRNAs), once thought to be nonfunctional, have recently been shown to participate in the multilevel regulation of transcriptional, posttranscriptional and epigenetic modifications and to play important roles in various biological processes, including immune responses. However, the expression and roles of lncRNAs in invertebrates, especially nonmodel organisms, remain poorly understood. In this study, by comparing a transcriptome to the PfIRF-2 genomic structure, we identified lncIRF-2 in the PfIRF-2 genomic intron. The results of the RNA interference (RNAi) and the nucleus grafting experiments indicated that PfIRF-2 might have a negative regulatory effect on lncIRF-2, and PfIRF-2 and lncIRF-2 may have a positive regulatory effect on PfIL-17. Additionally, lncIRF-2, PfIRF-2 and PfIL-17 were involved in responses to the nucleus graft. These results will enhance the knowledge of lncIRF-2, IRF-2, and IL-17 functions in both pearl oysters and other invertebrates.
源URL[http://ir.scsio.ac.cn/handle/344004/17630]  
专题南海海洋研究所_中科院海洋生物资源可持续利用重点实验室
作者单位1.Liu, Wen-guang
2.Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Prov Key Lab Appl Marine Biol, South China Sea Inst Oceanol, 164 West Xingang Rd, Guangzhou 510301, Guangdong, Peoples R China
3.He, Mao-Xian
4.[Huang, Xian-De
5.Dai, Jia-ge
6.Lin, Ke-tao
7.Liu, Mei
8.South China Agr Univ, Coll Marine Sci, 483 Wushan Rd, Guangzhou 510642, Guangdong, Peoples R China
9.[Huang, Xian-De
10.Zhang, Hua
推荐引用方式
GB/T 7714
Zhang, Hua,Huang, Xian-De,Dai, Jia-ge,et al. Regulation of IL-17 by lncRNA of IRF-2 in the pearl oyster[J]. FISH & SHELLFISH IMMUNOLOGY,2018,81:108, 112.
APA Zhang, Hua.,Huang, Xian-De.,Dai, Jia-ge.,Lin, Ke-tao.,Liu, Mei.,...&Zhao, Mi.(2018).Regulation of IL-17 by lncRNA of IRF-2 in the pearl oyster.FISH & SHELLFISH IMMUNOLOGY,81,108.
MLA Zhang, Hua,et al."Regulation of IL-17 by lncRNA of IRF-2 in the pearl oyster".FISH & SHELLFISH IMMUNOLOGY 81(2018):108.

入库方式: OAI收割

来源:南海海洋研究所

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