alpha-Glucosidase Inhibitors: Diphenyl Ethers and Phenolic Bisabolane Sesquiterpenoids from the Mangrove Endophytic Fungus Aspergillus flavus QQSG-3
文献类型：期刊论文
| 作者 | Wu, Yingnan; Huang, Xishan; Chen, Yan2; Pan, Yahong; Liu, Zhaoming3; She, Zhigang2; Yan, Tao1; Cao, Wenhao1 |
| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2018 |
| 卷号 | 16期号:9页码:307 |
| 关键词 | alpha-glucosidase inhibitors mangrove endophytic fungus Aspergillus flavus |
| ISSN号 | 1660-3397 |
| 英文摘要 | Two new diphenyl ethers (1 and 2) and four new phenolic bisabolane sesquiterpenoids (3-6), together with five known related derivatives, were isolated from the culture of the endophytic fungus Aspergillus flavus QQSG-3 obtained from a fresh branch of Kandelia obobata, which was collected from Huizhou city in the province of Guangdong, China. The structures of compounds 1-6 were determined by analyzing NMR and HRESIMS data. The absolute configurations of 5 and 6 were assigned by comparing their experimental ECD spectra with those reported for similar compounds in the literature. All isolates were evaluated for their -glucosidase inhibitory activity, of which compounds 3, 5, 10, and 11 showed strong inhibitory effects with IC50 values in the range of 1.5-4.5 M. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17638]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Guangdong Inst Microbiol, State Key Lab Appl Microbiol Southern China, Guangzhou 510075, Guangdong, Peoples R China 2.Sun Yat Sen Univ, Sch Chem, Guangzhou 510275, Guangdong, Peoples R China 3.Sun Yat Sen Univ, Sch Marine Sci, South China Sea Bioresource Exploitat & Utilizat, Guangzhou 510006, Guangdong, Peoples R China 4.Chinese Acad Sci, CAS Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510301, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wu, Yingnan,Huang, Xishan,Chen, Yan,et al. alpha-Glucosidase Inhibitors: Diphenyl Ethers and Phenolic Bisabolane Sesquiterpenoids from the Mangrove Endophytic Fungus Aspergillus flavus QQSG-3[J]. MARINE DRUGS,2018,16(9):307. |
| APA | Wu, Yingnan.,Huang, Xishan.,Chen, Yan.,Pan, Yahong.,Liu, Zhaoming.,...&Cao, Wenhao.(2018).alpha-Glucosidase Inhibitors: Diphenyl Ethers and Phenolic Bisabolane Sesquiterpenoids from the Mangrove Endophytic Fungus Aspergillus flavus QQSG-3.MARINE DRUGS,16(9),307. |
| MLA | Wu, Yingnan,et al."alpha-Glucosidase Inhibitors: Diphenyl Ethers and Phenolic Bisabolane Sesquiterpenoids from the Mangrove Endophytic Fungus Aspergillus flavus QQSG-3".MARINE DRUGS 16.9(2018):307. |
入库方式： OAI收割
来源：南海海洋研究所
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