Spiro-Phthalides and Isocoumarins Isolated from the Marine-Sponge-Derived Fungus Setosphaeria sp SCSIO41009
文献类型：期刊论文
| 作者 | Yang, Jie1; Zhou, Xuefeng; Yang, Bin; Wang, Junfeng; Liu, Yonghong2; Pang, Xiaoyan2; Lin, Xiuping |
| 刊名 | JOURNAL OF NATURAL PRODUCTS
 |
| 出版日期 | 2018 |
| 卷号 | 81期号:8页码:1860 |
| ISSN号 | 0163-3864 |
| 英文摘要 | Fourteen new polyketides classified as four phthalides, setosphalides A and B, 5-O-desmethyl- colletotrialide, and (S)-colletotrialide (1-4), three isocoumar-in derivatives, exserolides I-K (5-7), four pyrones, setosphapyrones A-D (8-11), one furanone (12), and two depsidones (13 and 14), along with 17 known polyketides were isolated from cultures of the sponge-derived fungus Setosphaeria sp. SCSIO41009. The structures and absolute Setosphaeria sp. SCSIO41009 configurations of these new compounds (1-14) were determined by spectroscopic analyses, X-ray diffraction, chiral-phase HPLC analysis, modified Mosher's method, and comparison of ECD spectra to calculations. Setosphalides A (1) and B (2) are the first examples possessing a 5,5 spiroketal skeleton in phthalide derivatives. Botryorhodines I (13) and J (14) showed moderate antifungal activities against the phytopathogenic fungi Colletotrichum asianum and Colletotrichum acutatum. Compound 18 (7-O-demethylmonocerin) exhibited potent radical scavenging activity against DPPH. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17650]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Univers Chinese Acad Sci, Beijing 100049, Peoples R China 2.Chinese Acad Sci, Key Lab Trop Marine Bioresources & Ecol, Guangdong Key Lab Marine Mat Med, RNAM Ctr Marine Microbiol,South China Sea Inst Oc, Guangzhou 510220, Guangdong, Peoples R China 3.Southern Med Univ, Guangdong Prov Key Lab New Drug Screening, Guangzhou Key Lab Drug Res Emerging Virus Prevent, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Jie,Zhou, Xuefeng,Yang, Bin,et al. Spiro-Phthalides and Isocoumarins Isolated from the Marine-Sponge-Derived Fungus Setosphaeria sp SCSIO41009[J]. JOURNAL OF NATURAL PRODUCTS,2018,81(8):1860, 1868. |
| APA | Yang, Jie.,Zhou, Xuefeng.,Yang, Bin.,Wang, Junfeng.,Liu, Yonghong.,...&Lin, Xiuping.(2018).Spiro-Phthalides and Isocoumarins Isolated from the Marine-Sponge-Derived Fungus Setosphaeria sp SCSIO41009.JOURNAL OF NATURAL PRODUCTS,81(8),1860. |
| MLA | Yang, Jie,et al."Spiro-Phthalides and Isocoumarins Isolated from the Marine-Sponge-Derived Fungus Setosphaeria sp SCSIO41009".JOURNAL OF NATURAL PRODUCTS 81.8(2018):1860. |
入库方式： OAI收割
来源：南海海洋研究所
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