Molecular identification of GnIH and its potential role in reproductive physiology and male pregnancy of the lined seahorse (Hippocampus erectus)
文献类型：期刊论文
| 作者 | Zhang, Huixian; Chen, Lingzhen1; Zhang, Bo1; Lin, Qiang1 |
| 刊名 | GENERAL AND COMPARATIVE ENDOCRINOLOGY
 |
| 出版日期 | 2019 |
| 卷号 | 279页码:196 |
| 关键词 | Gonadotropin-inhibitory hormone LPXRF Pregnancy Seahorse Teleost |
| ISSN号 | 0016-6480 |
| DOI | 10.1016/j.ygcen.2019.04.018 |
| 英文摘要 | The gonadotropin-inhibitory hormone (GnIH) plays a negative role in the hypothalamic-pituitary-gonadal (HPG) axis by inhibiting gonadotropin secretion in vertebrates. Male pregnancy and ovoviviparous behavior are unique phenomena among vertebrates. To better understand the neuroendocrine regulatory mechanisms in ovoviviparous fish with male pregnancy, we identified the orthologous GnIH gene in the lined seahorse (Hippocampus erectus). The full-length cDNA of the GnIH precursor was 658 base pairs with an open reading frame of 528 base pairs that encoded a 175-amino acid prepro-GnIH peptide. The seahorse GnIH precursor contained two putative LPXRFamide peptides. Both seahorse LPXRFa-1 and LPXRFa-2 were found to be unique among vertebrates. The synteny blocks of GnIH gene loci were conserved in mammals and teleosts. Tissue distribution analysis revealed that seahorse GnIH mRNA was mainly expressed in the hypothalamus, with relatively high levels observed in the brood pouch. The expression patterns of seahorse GnIH during different reproductive stages and pregnancy stages were also detected, and GnIH mRNA expression was significantly reduced during the early puberty stage. In addition, GnIH mRNA expression was significantly increased during the pregnancy stage compared to non-pregnancy stages. In summary, our results reveal the existence of GnIH in ovoviviparous fish and suggest its involvement in regulation of reproductive behavior and male pregnancy in the male seahorse. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17805]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Chinese Acad Sci, Inst South China Sea Ecol & Environm Engn, Guangdong Prov Key Lab Appl Marine Biol Lamb, South China Sea Inst Oceanol,CAS Key Lab Trop Mar, Guangzhou, Guangdong, Peoples R China 2.Univ Chinese Acad Sci, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Huixian,Chen, Lingzhen,Zhang, Bo,et al. Molecular identification of GnIH and its potential role in reproductive physiology and male pregnancy of the lined seahorse (Hippocampus erectus)[J]. GENERAL AND COMPARATIVE ENDOCRINOLOGY,2019,279:196, 202. |
| APA | Zhang, Huixian,Chen, Lingzhen,Zhang, Bo,&Lin, Qiang.(2019).Molecular identification of GnIH and its potential role in reproductive physiology and male pregnancy of the lined seahorse (Hippocampus erectus).GENERAL AND COMPARATIVE ENDOCRINOLOGY,279,196. |
| MLA | Zhang, Huixian,et al."Molecular identification of GnIH and its potential role in reproductive physiology and male pregnancy of the lined seahorse (Hippocampus erectus)".GENERAL AND COMPARATIVE ENDOCRINOLOGY 279(2019):196. |
入库方式： OAI收割
来源：南海海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。