A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample
文献类型：期刊论文
| 作者 | Tao, Huaming2; Li, Yunqiu1; Lin, Xiuping; Zhou, Xuefeng; Dong, Junde; Liu, Yonghong; Yang, Bin |
| 刊名 | NATURAL PRODUCT COMMUNICATIONS
 |
| 出版日期 | 2018 |
| 卷号 | 13期号:12页码:1629 |
| 关键词 | Marine-derived fungus Aspergillus Steroid Mycotoxins |
| ISSN号 | 1934-578X |
| 英文摘要 | Chemical investigation of the fungus Aspergillus sp. SCSIO41211 derived of mangrove sediment sample afforded a ergostane-type pentacyclic steroid, (22S, 23R)-12 alpha,14 alpha,23 alpha-trihydroxy-16,22-epoxy-ergosta-4,8-dien-3,11-dione (1), together with seven known compounds, flavacol (2), aspergilliamide (3), ochratoxin A methyl ester (4), ochratoxin A ethyl ester (5), dihydroaspyrone (6), aspilactonol E (7) and aspilactonol F (8). The structures were determined on the basis of NMR and MS analysis. The isolated compounds were tested for their antiviral activity against H3N2 and EV71 viruses, cytotoxic, and antituberculosis effects. Among them, compounds 2 and 5 showed significant cytotoxicity against ten human cancer cell lines. None of the compounds displayed a significant antiviral activity against H3N2 and EV71 viruses nor antimycobacterial activities. |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/17931]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 作者单位 | 1.Southern Med Univ, Sch Tradit Chinese Med, Guangzhou 510515, Guangdong, Peoples R China 2.Chinese Acad Sci, South China Sea Inst Oceanol, Guangdong Key Lab Marine Mat Med, Key Lab Trop Marine Bioresources & Ecol, Guangzhou 510301, Guangdong, Peoples R China 3.Guilin Med Univ, Coll Pharmaceut Sci, Guilin 541004, Peoples R China |
| 推荐引用方式 GB/T 7714 | Tao, Huaming,Li, Yunqiu,Lin, Xiuping,et al. A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample[J]. NATURAL PRODUCT COMMUNICATIONS,2018,13(12):1629, 1631. |
| APA | Tao, Huaming.,Li, Yunqiu.,Lin, Xiuping.,Zhou, Xuefeng.,Dong, Junde.,...&Yang, Bin.(2018).A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample.NATURAL PRODUCT COMMUNICATIONS,13(12),1629. |
| MLA | Tao, Huaming,et al."A New Pentacyclic Ergosteroid from Fungus Aspergillus sp. SCSIO41211 Derived of Mangrove Sediment Sample".NATURAL PRODUCT COMMUNICATIONS 13.12(2018):1629. |
入库方式： OAI收割
来源：南海海洋研究所
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