Structure elucidation and immunological activity of a novel polysaccharide from the fruit bodies of an edible mushroom, Sarcodon aspratus (Berk.) S. Ito.
文献类型：期刊论文
| 作者 | pengfeitu@vip.163.com; Han, CX; Tu, PF; Han, XQ; Chai, XY; Jia, YM |
| 刊名 | INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
 |
| 出版日期 | 2010 |
| 卷号 | 47期号:3页码:420-424 |
| 关键词 | Sarcodon AS.ratuS.(Berk.) S. Ito. Edible Mushroom Polysaccharide Glucan Immunological Activity |
| ISSN号 | 0141-8130 |
| 英文摘要 | A water-soluble polysaccharide with a molar weight of 4.3 x 10(5) Da, termed as HBP was isolated from the fruit bodies of an edible mushroom, Sarcodon aspratus (Berk.) S. Ito. Composition, methylation analysis, Fourier transform infrared spectroscopy, and nuclear magnetic resonance spectroscopy experiments were conducted to elucidate its structure. The results indicated that HBP is a glucan featuring a backbone of (1 -> 6)-linked-beta-D-glucopyranosyl residues, which occasionally branched at O-3 position on along the backbone and substituted by the side chains that consisting of (1 -> 3)-linked-beta-D-glucopyranosyl, (1 -> 4)-linked-beta-D-glucopyranosyl and non-reducing end beta-D-glucopyranosyl residues. Immunological activity evaluation by H-3-thymidine incorporation method revealed that HBP can significantly stimulate the proliferation of the cultured mice spleen lymphocyte in a dose-dependent manner, thus, HBP is a promising potential immunomodulator that can be used as healthcare food or medicine against pathogens and tumors. (C) 2010 Elsevier B.V. All rights reserved. |
| 学科主题 | Biochemistry & Molecular Biology |
| URL标识 | 查看原文 |
| 资助项目 | LMB |
| WOS记录号 | WOS:000281490500016 |
| 公开日期 | 2011-07-02 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/3780]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | pengfeitu@vip.163.com |
| 推荐引用方式 GB/T 7714 | pengfeitu@vip.163.com,Han, CX,Tu, PF,et al. Structure elucidation and immunological activity of a novel polysaccharide from the fruit bodies of an edible mushroom, Sarcodon aspratus (Berk.) S. Ito.[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2010,47(3):420-424. |
| APA | pengfeitu@vip.163.com,Han, CX,Tu, PF,Han, XQ,Chai, XY,&Jia, YM.(2010).Structure elucidation and immunological activity of a novel polysaccharide from the fruit bodies of an edible mushroom, Sarcodon aspratus (Berk.) S. Ito..INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,47(3),420-424. |
| MLA | pengfeitu@vip.163.com,et al."Structure elucidation and immunological activity of a novel polysaccharide from the fruit bodies of an edible mushroom, Sarcodon aspratus (Berk.) S. Ito.".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 47.3(2010):420-424. |
入库方式： OAI收割
来源：南海海洋研究所
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