Trichodermaketones A-D and 7-O-Methylkoninginin D from the Marine Fungus Trichoderma koningii
文献类型:期刊论文
作者 | Chen, CX; zhanglixin@im.ac.cn; Zhang, LX; Chen, XP; Liu, HW; Gao, H; Liu, M; Bian, J; Liu, XY; Sun, N |
刊名 | JOURNAL OF NATURAL PRODUCTS
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出版日期 | 2010 |
卷号 | 73期号:5页码:806-810 |
ISSN号 | 0163-3864 |
英文摘要 | Five new polyketide derivatives, 7-O-methylkoninginin D (1) and trichodermaketones A-D (2-5), together with four known compounds, koninginins A, D, E, and F, were isolated from the marine-derived fungus Trichoderma koningii. Trichodermaketones A (2) and B (3) are unprecedented polyketides with a bistetrafuran-containing tricyclic skeleton. The chemical structures and absolute configurations of compounds 1-5 were elucidated by comparing with literature data and extensive spectroscopic methods, including 2D NMR and CD spectroscopic analysis. Compounds 1-5 were evaluated for action against bacteria and fungi and for synergistic antifungal activity. Compound 2 showed synergistic antifungal activity against Candida albicans with 0.05 mu g/mL ketoconazole. |
学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
URL标识 | 查看原文 |
资助项目 | LMB |
WOS记录号 | WOS:000278080900003 |
公开日期 | 2011-07-02 |
源URL | [http://ir.scsio.ac.cn/handle/344004/3826] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
通讯作者 | zhanglixin@im.ac.cn |
推荐引用方式 GB/T 7714 | Chen, CX,zhanglixin@im.ac.cn,Zhang, LX,et al. Trichodermaketones A-D and 7-O-Methylkoninginin D from the Marine Fungus Trichoderma koningii[J]. JOURNAL OF NATURAL PRODUCTS,2010,73(5):806-810. |
APA | Chen, CX.,zhanglixin@im.ac.cn.,Zhang, LX.,Chen, XP.,Liu, HW.,...&Song, FH.(2010).Trichodermaketones A-D and 7-O-Methylkoninginin D from the Marine Fungus Trichoderma koningii.JOURNAL OF NATURAL PRODUCTS,73(5),806-810. |
MLA | Chen, CX,et al."Trichodermaketones A-D and 7-O-Methylkoninginin D from the Marine Fungus Trichoderma koningii".JOURNAL OF NATURAL PRODUCTS 73.5(2010):806-810. |
入库方式: OAI收割
来源:南海海洋研究所
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