A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species
文献类型:期刊论文
作者 | Huang, RM; Ma, W; Dong, JD; Zhou, XF; Xu, TH; Lee, KJ; Yang, XW; Xu, SH; Liu, YH; huang_riming@hotmail.com |
刊名 | MOLECULES
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出版日期 | 2010 |
卷号 | 15期号:2页码:871-877 |
关键词 | Marine Sponge CallySp.ngia Sp. Diazepine Callysponine |
ISSN号 | 1420-3049 |
英文摘要 | A new 1,4-diazepine, callysponine (1), was isolated from a South China Sea Callyspongia sp. marine sponge, together with four known proline-based diketopiperazines: cyclo-(S-Pro-R-Leu) (2), cyclo-(S-Pro-R-Val) (3), cyclo-(S-Pro-R-Ala) (4), and cyclo-(S-Pro-R-Tyr) (5). The new structure was determined on the basis of NMR and MS analysis, and the absolute stereochemistry was defined by NOESY spectroscopy and optical rotation. The structures of the known compounds were identified by comparison of their spectroscopic data with those reported in the literature. Callysponine (1) did not inhibit the growth of HepG2 (hepatoma carcinoma cell), A549 (lung carcinoma cell), and HeLa (cervical cancer cell) cell lines. |
学科主题 | Chemistry, Organic |
URL标识 | 查看原文 |
资助项目 | LMB |
WOS记录号 | WOS:000274929200024 |
公开日期 | 2011-07-02 |
源URL | [http://ir.scsio.ac.cn/handle/344004/3896] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
通讯作者 | huang_riming@hotmail.com; txush@jnu.edu.cn; yonghongliu@scsio.ac.cn |
推荐引用方式 GB/T 7714 | Huang, RM,Ma, W,Dong, JD,et al. A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species[J]. MOLECULES,2010,15(2):871-877. |
APA | Huang, RM.,Ma, W.,Dong, JD.,Zhou, XF.,Xu, TH.,...&yonghongliu@scsio.ac.cn.(2010).A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species.MOLECULES,15(2),871-877. |
MLA | Huang, RM,et al."A New 1,4-Diazepine from South China Sea Marine Sponge Callyspongia Species".MOLECULES 15.2(2010):871-877. |
入库方式: OAI收割
来源:南海海洋研究所
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