In vitro antitumor activity of triterpenes from Ceriops tagal
文献类型:期刊论文
作者 | Wang, YS; He, L; yswang@scsio.ac.cn; Wang, QJ |
刊名 | NATURAL PRODUCT RESEARCH
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出版日期 | 2007 |
卷号 | 21期号:14页码:1228-1233 |
关键词 | Ceriops Tagal Rhizophoraceae Antitumor Triterpenes |
ISSN号 | 1478-6419 |
英文摘要 | The embryo of Ceriops tagal was extracted with 95% ethanol at room temperature, and four triterpenes (1-4) were separated from this extract. For the first time these triterpenes were the separated from this plant. Compounds (1-4) were tested in vitro for antitumor activity against three cell lines (human liver cancer cell (H-7402), human B-lymphoblastoid cell (Raji). and human cervical carcinoma cell (Hela)). Compounds I and 3 were effective to inhibit cell proliferation and growth of H-7402 and Hela. the IC50 of them on H-7402 were 14.42 mu g mL(-1) and 9.97 mu g mL(-1). and the IC50 of them on Hela were 11.84 mu g mL(-1) and 11.32 mu g mL(-1) All compounds 1-4 were not effective to inhibit cell proliferation and growth of Raji. The effects of compound 4 on inhibiting proliferation and growth of these three cancer cells was also not obvious. |
学科主题 | Chemistry, Applied ; Chemistry, Medicinal |
URL标识 | 查看原文 |
资助项目 | LMB |
WOS记录号 | WOS:000252185200002 |
公开日期 | 2011-07-03 |
源URL | [http://ir.scsio.ac.cn/handle/344004/4902] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
通讯作者 | yswang@scsio.ac.cn |
推荐引用方式 GB/T 7714 | Wang, YS,He, L,yswang@scsio.ac.cn,et al. In vitro antitumor activity of triterpenes from Ceriops tagal[J]. NATURAL PRODUCT RESEARCH,2007,21(14):1228-1233. |
APA | Wang, YS,He, L,yswang@scsio.ac.cn,&Wang, QJ.(2007).In vitro antitumor activity of triterpenes from Ceriops tagal.NATURAL PRODUCT RESEARCH,21(14),1228-1233. |
MLA | Wang, YS,et al."In vitro antitumor activity of triterpenes from Ceriops tagal".NATURAL PRODUCT RESEARCH 21.14(2007):1228-1233. |
入库方式: OAI收割
来源:南海海洋研究所
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