Two New Spirobiflavonoids from Abies chensiensis with Moderate NO Production Inhibitory Activity
文献类型：期刊论文
| 作者 | Zhang, WD; Li, YL; Huang, DS; Yang, XW; Li, SM; Tang, J; Tian, JM; Peng, XY; yangxw76@163.com |
| 刊名 | PLANTA MEDICA
 |
| 出版日期 | 2009 |
| 卷号 | 75期号:14页码:1534-1537 |
| 关键词 | Abies Chensiensis Pinaceae Spirobiflavonoids Larixinol Raw 264.7 Macrophages No |
| ISSN号 | 0032-0943 |
| 英文摘要 | Phytochemical investigation of the aerial parts of Abies chensiensis afforded two new (compounds 2 and 3) and 27 known compounds, including the related compound larixinol (1). The structures of spirobiflavonoids 1-3 were established using 1D and 2D NMR spectroscopic techniques. In addition, the structure of larixinol (1) was confirmed by X-ray crystallographic analysis. Compounds 1-3 were evaluated for inhibitory activities against LPS-induced NO production in macrophages. Larixinol (1) showed moderate effects, with an IC50 value of 60.0 mu g/mL. In addition, it did not show any cytotoxicity on RAW 264.7 macrophages at 100 mu g/mL. |
| 学科主题 | Plant Sciences ; Chemistry, Medicinal ; Pharmacology & Pharmacy |
| URL标识 | 查看原文 |
| 资助项目 | LMB |
| WOS记录号 | WOS:000272183500014 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5046]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | yangxw76@163.com |
| 推荐引用方式 GB/T 7714 | Zhang, WD,Li, YL,Huang, DS,et al. Two New Spirobiflavonoids from Abies chensiensis with Moderate NO Production Inhibitory Activity[J]. PLANTA MEDICA,2009,75(14):1534-1537. |
| APA | Zhang, WD.,Li, YL.,Huang, DS.,Yang, XW.,Li, SM.,...&yangxw76@163.com.(2009).Two New Spirobiflavonoids from Abies chensiensis with Moderate NO Production Inhibitory Activity.PLANTA MEDICA,75(14),1534-1537. |
| MLA | Zhang, WD,et al."Two New Spirobiflavonoids from Abies chensiensis with Moderate NO Production Inhibitory Activity".PLANTA MEDICA 75.14(2009):1534-1537. |
入库方式： OAI收割
来源：南海海洋研究所
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