The Interleukin-18 Inhibitory Activities of Echinocystic Acid and its Saponins from Impatiens pritzellii var. hupehensis
文献类型：期刊论文
| 作者 | Liu, Y; zpeng_1979@163.com; Wu, JZ; Zhou, XF; Tang, L; Zhang, P; Zhao, XY; Pi, HF; Zhang, YH; Ruan, HL |
| 刊名 | ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES
 |
| 出版日期 | 2009 |
| 卷号 | 64期号:40669页码:369-372 |
| 关键词 | Echinocystic Acid Impatiens Pritzellii Var. Hupehensis Interleukin-18 |
| ISSN号 | 0939-5075 |
| 英文摘要 | Echinocystic acid (1), an echinocystic acid saponin, 2, and four of its ester saponins, 3-6, obtained from the active fraction of Impatiens pritzellii var. hupehensis, an traditional Chinese medicine for rheumatoid arthritis, were investigated for their effects on lipopolysaccharide (LPS)-induced interleukin (IL)-18 in human peripheral blood mononuclear cells. Three of them,1, 2 and 6, showed obvious activity to inhibit the production of IL-18, especially the ester saponins with a sugar chain at C-28, 6. Structure-activity relationships are discussed in brief. |
| 学科主题 | Biochemistry & Molecular Biology ; Pharmacology & Pharmacy |
| URL标识 | 查看原文 |
| 资助项目 | LMB |
| WOS记录号 | WOS:000268826700011 |
| 公开日期 | 2011-07-03 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/5086]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | zpeng_1979@163.com |
| 推荐引用方式 GB/T 7714 | Liu, Y,zpeng_1979@163.com,Wu, JZ,et al. The Interleukin-18 Inhibitory Activities of Echinocystic Acid and its Saponins from Impatiens pritzellii var. hupehensis[J]. ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES,2009,64(40669):369-372. |
| APA | Liu, Y.,zpeng_1979@163.com.,Wu, JZ.,Zhou, XF.,Tang, L.,...&Ruan, HL.(2009).The Interleukin-18 Inhibitory Activities of Echinocystic Acid and its Saponins from Impatiens pritzellii var. hupehensis.ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES,64(40669),369-372. |
| MLA | Liu, Y,et al."The Interleukin-18 Inhibitory Activities of Echinocystic Acid and its Saponins from Impatiens pritzellii var. hupehensis".ZEITSCHRIFT FUR NATURFORSCHUNG SECTION C-A JOURNAL OF BIOSCIENCES 64.40669(2009):369-372. |
入库方式： OAI收割
来源：南海海洋研究所
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