Antibacterial and antilarval compounds from marine bacterium Pseudomonas rhizosphaerae
文献类型:期刊论文
作者 | Zhang, S; Qi, SH; Xu, Y; Gao, J; Qian, PY; shuhuaqi2001@yahoo.com |
刊名 | ANNALS OF MICROBIOLOGY
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出版日期 | 2009 |
卷号 | 59期号:2页码:229-233 |
关键词 | Marine Bacterium Pseudomonas Rhizosphaerae Antibacterial Antilarval Diketopiperazine |
ISSN号 | 1590-4261 |
英文摘要 | In order to obtain non-toxic, antifouling natural products from marine organisms, we studied on the marine bacterium Pseudomonas rhizosphaerae isolated from deep sea sediment. Bioassay-guided column chromatography techniques were used to separate and purify compounds. Extensive spectral analyses including 1D NMR spectra and GC-MS were employed for structure elucidation of the compounds. Antibacterial activity of the isolated compounds towards eight marine bacterial strains was measures by optical density, while antilarval activity was evaluated in settlement inhibition assays with laboratory-reared Balanus amphitrite and Bugula neritina larvae. In total, nine compounds including six diketopiperazine were obtained. Among them, cyclo-(Tyr-Pro), cyclo-(Tyr-Ile), cyclo-(Phe-Pro), cyclo-(Val-Pro), 3-phenyl-2-propenoic acid, and uracil had various antibacterial activities towards five marine fouling bacteria, furthermore, bis(2-ethylhexyl)phthalate, cyclo-(Tyr-Ile), cyclo-(Phe-Pro), cyclo-(Val-Pro), and 3-phenyl-2-propenoic acid showed antilarval effect on larval settlement of barnacle Balanus amphitrite and bryozoan Bugula neritina. The results suggested that marine bacterium Pseudomonas rhizosphaerae could produce potent antibacterial and antilarval diketopiperazine and benzene-type secondary metabolites. |
学科主题 | Biotechnology & Applied Microbiology ; Microbiology |
URL标识 | 查看原文 |
资助项目 | LMB |
WOS记录号 | WOS:000267606200005 |
公开日期 | 2011-07-03 |
源URL | [http://ir.scsio.ac.cn/handle/344004/5102] ![]() |
专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
通讯作者 | shuhuaqi2001@yahoo.com |
推荐引用方式 GB/T 7714 | Zhang, S,Qi, SH,Xu, Y,et al. Antibacterial and antilarval compounds from marine bacterium Pseudomonas rhizosphaerae[J]. ANNALS OF MICROBIOLOGY,2009,59(2):229-233. |
APA | Zhang, S,Qi, SH,Xu, Y,Gao, J,Qian, PY,&shuhuaqi2001@yahoo.com.(2009).Antibacterial and antilarval compounds from marine bacterium Pseudomonas rhizosphaerae.ANNALS OF MICROBIOLOGY,59(2),229-233. |
MLA | Zhang, S,et al."Antibacterial and antilarval compounds from marine bacterium Pseudomonas rhizosphaerae".ANNALS OF MICROBIOLOGY 59.2(2009):229-233. |
入库方式: OAI收割
来源:南海海洋研究所
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