Cytotoxic indole diketopiperazines from the deep sea-derived fungus Acrostalagmus luteoalbus SCSIO F457
文献类型：期刊论文
| 作者 | Zhang, WM; zhsimd@scsio.ac.cn; Zhang, S; Li, J; Tian, XP; Chen, YC; Shi, XF; Huang, Z; Wang, FZ |
| 刊名 | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
 |
| 出版日期 | 2012 |
| 卷号 | 22期号:23页码:7265-7267 |
| 关键词 | Indole Diketopiperazine Cytotoxicity Acrostalagmus Luteoalbus Marine Fungi Deep-sea Sediment |
| ISSN号 | 0960-894X |
| 英文摘要 | Two new indole diketopiperazines, namely luteoalbusins A-B (1-2), along with eight known ones (3-10), were isolated from the fungus Acrostalagmus luteoalbus SCSIO F457 originated from deep-sea sediment. Their structures were determined by 1D/2D NMR, MS, and CD data analyses. Each of these compounds was evaluated for their cytotoxic activities against SF-268, MCF-7, NCI-H460, and HepG-2 cell lines, and compounds 1-5 showed significant cytotoxicties against all four cancer cell lines. Moreover, new compounds 1 and 2 had more potent cytotoxicity than the other ones and cisplatin. (C) 2012 Published by Elsevier Ltd. |
| 学科主题 | Chemistry, Medicinal ; Chemistry, Organic |
| 资助项目 | LMB |
| 语种 | 英语 |
| WOS记录号 | WOS:000310583100056 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/9742]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | zhsimd@scsio.ac.cn |
| 推荐引用方式 GB/T 7714 | Zhang, WM,zhsimd@scsio.ac.cn,Zhang, S,et al. Cytotoxic indole diketopiperazines from the deep sea-derived fungus Acrostalagmus luteoalbus SCSIO F457[J]. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,2012,22(23):7265-7267. |
| APA | Zhang, WM.,zhsimd@scsio.ac.cn.,Zhang, S.,Li, J.,Tian, XP.,...&Wang, FZ.(2012).Cytotoxic indole diketopiperazines from the deep sea-derived fungus Acrostalagmus luteoalbus SCSIO F457.BIOORGANIC & MEDICINAL CHEMISTRY LETTERS,22(23),7265-7267. |
| MLA | Zhang, WM,et al."Cytotoxic indole diketopiperazines from the deep sea-derived fungus Acrostalagmus luteoalbus SCSIO F457".BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 22.23(2012):7265-7267. |
入库方式： OAI收割
来源：南海海洋研究所
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