Molecular cloning and characterization of class I NF-kappa B transcription factor from pearl oyster (Pinctada fucata)
文献类型：期刊论文
| 作者 | Wu, SZ; Huang, XD; Liu, WG; Guan, YY; Shi, Y; Wang, Q; Zhao, M; hmx@scsio.ac.cn; He, MX |
| 刊名 | FISH & SHELLFISH IMMUNOLOGY
 |
| 出版日期 | 2012 |
| 卷号 | 33期号:3页码:659-666 |
| 关键词 | Pearl Oyster Class i Nif Kappa b Transcription Factor Gene Cloning Immunity Response |
| ISSN号 | 1050-4648 |
| 英文摘要 | NF-kappa B transcription factors play central roles in many important physiological and pathological processes including innate immune responses. Here we report the cloning of an NF-kappa B transcription factor. PfRelish from pearl oyster Pinctada fucata, one of the most important bivalve mollusks for seawater pearl production. PfRelish full-length cDNA is 3916 bp with an open reading frame of 3558 bp encoding a putative protein of 1186 amino acids. The deduced PfRelish contains a N-terminal RHD, a nucleus localization signal, an I kappa B-like domain with six ankyrin repeats and a death domain at the C-terminus, which is similar to class I NF-kappa B transcription factors. Comparison and phylogenetic analysis revealed that class I NF-kappa Bs in mollusks including PfRelish might have most distant relationship to the arthropod Relish. Further expression analysis showed that PfRelish was apparently upregulated after Vibrio alginolyticus injection, which suggested that PfRelish was involved in the immune response to V. alginolyticus. (C) 2012 Elsevier Ltd. All rights reserved. |
| 学科主题 | Fisheries ; Immunology ; Marine & Freshwater Biology ; Veterinary Sciences |
| 资助项目 | LMB |
| 语种 | 英语 |
| WOS记录号 | WOS:000308057700025 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/9822]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | hmx@scsio.ac.cn |
| 推荐引用方式 GB/T 7714 | Wu, SZ,Huang, XD,Liu, WG,et al. Molecular cloning and characterization of class I NF-kappa B transcription factor from pearl oyster (Pinctada fucata)[J]. FISH & SHELLFISH IMMUNOLOGY,2012,33(3):659-666. |
| APA | Wu, SZ.,Huang, XD.,Liu, WG.,Guan, YY.,Shi, Y.,...&He, MX.(2012).Molecular cloning and characterization of class I NF-kappa B transcription factor from pearl oyster (Pinctada fucata).FISH & SHELLFISH IMMUNOLOGY,33(3),659-666. |
| MLA | Wu, SZ,et al."Molecular cloning and characterization of class I NF-kappa B transcription factor from pearl oyster (Pinctada fucata)".FISH & SHELLFISH IMMUNOLOGY 33.3(2012):659-666. |
入库方式： OAI收割
来源：南海海洋研究所
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