Two New Coumarins from Micromelum falcatum with Cytotoxicity and Brine Shrimp Larvae Toxicity
文献类型：期刊论文
| 作者 | liqx81@163.com; zhsimd@scsio.ac.cn; tj6188@sina.com; lq_11@hotmail.com; yinhao@scsio.ac.cn; whhe@scsio.ac.cn; luoxm163@sina.com; Zhang, S; Huang, YZ; Liu, Q |
| 刊名 | MOLECULES
 |
| 出版日期 | 2012 |
| 卷号 | 17期号:6页码:6944-6952 |
| 关键词 | Micromelum Falcatum Coumarins Brine Shrimp Larvae Toxicity Cytotoxicity Antibacterial Activity |
| ISSN号 | 1420-3049 |
| 英文摘要 | Two new coumarins, 7-methoxy-8-(2-hydroxmethyl-1-O-isovaleryl-4-butenyl)coumarin (1) and 7-methoxy-8-(1-hydroxy-2-O-beta-glucopyranosyl-3-methyl-4-butene-1-yl) coumarin (2), and twelve known coumarins 3-14 were isolated from the stem bark of Micromelum falcatum. The structures of compounds 1-14 were elucidated by extensive spectroscopic data analyses. The toxicity of compounds 1-14 was tested using a brine shrimp assay and in vitro antiproliferative assay against mammary cancer (F10) and lung cancer (HvEvc) cell lines by the MTT method. Some compounds had moderate activities. All compounds were also tested against the microorganisms Bacillus subtilis, Bacillus thuringiensis and Escherichia coli, but no activity was observed. |
| 学科主题 | Chemistry, Organic |
| 资助项目 | LMB |
| 语种 | 英语 |
| WOS记录号 | WOS:000305800400052 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/9884]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | liqx81@163.com; zhsimd@scsio.ac.cn; tj6188@sina.com; lq_11@hotmail.com; yinhao@scsio.ac.cn; whhe@scsio.ac.cn; luoxm163@sina.com |
| 推荐引用方式 GB/T 7714 | liqx81@163.com,zhsimd@scsio.ac.cn,tj6188@sina.com,et al. Two New Coumarins from Micromelum falcatum with Cytotoxicity and Brine Shrimp Larvae Toxicity[J]. MOLECULES,2012,17(6):6944-6952. |
| APA | liqx81@163.com.,zhsimd@scsio.ac.cn.,tj6188@sina.com.,lq_11@hotmail.com.,yinhao@scsio.ac.cn.,...&Luo, XM.(2012).Two New Coumarins from Micromelum falcatum with Cytotoxicity and Brine Shrimp Larvae Toxicity.MOLECULES,17(6),6944-6952. |
| MLA | liqx81@163.com,et al."Two New Coumarins from Micromelum falcatum with Cytotoxicity and Brine Shrimp Larvae Toxicity".MOLECULES 17.6(2012):6944-6952. |
入库方式： OAI收割
来源：南海海洋研究所
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