Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data
文献类型：期刊论文
| 作者 | Li, J; Liang, JL; Zhou, Y; Wu, J; Pan, JY; wwujun2003@yahoo.com; Li, MY |
| 刊名 | JOURNAL OF SEPARATION SCIENCE
 |
| 出版日期 | 2012 |
| 卷号 | 35期号:7页码:782-789 |
| 关键词 | Diarrhetic Shellfish Poisoning Toxin Profile Lc-ms Ms Nmr Okadaic Acid Diol Esters Prorocentrum Lima |
| ISSN号 | 1615-9306 |
| 英文摘要 | The marine dinoflagellate Prorocentrum lima can produce toxins of okadaic acid and its congeners, which are mainly responsible for diarrhetic shellfish poisoning syndrome. Since 1990s, cells of P. lima have been reported as epiphytes to seaweeds distributed along the coast of Hainan Island. However, its toxin profile has not hitherto been investigated. We report herein the first description and unequivocal evidence of diarrhetic shellfish poisoning toxin production in a cultured strain of P. lima isolated from the coast of Sanya, Hainan Island. Okadaic acid and its two longest diol esters, viz. okadaic acid-D10a and okadaic acid-D10b, have been characterized as the main diarrhetic shellfish poisoning toxin congeners of this strain by liquid chromatographytandem mass spectrometry and NMR spectroscopic data. Okadaic acid-D10a and okadaic acid-D10b are first identified by NMR spectroscopic data from the dinoflagellate P. lima. The simultaneous presence of okadaic acid-D10a and okadaic acid-D10b in P. lima enlarges the range of target molecules that must be considered in future diarrhetic shellfish poisoning monitoring programs of Hainan Island, China. |
| 学科主题 | Chemistry, Analytical |
| 资助项目 | LMB |
| 语种 | 英语 |
| WOS记录号 | WOS:000303200200002 |
| 公开日期 | 2013-08-28 |
| 源URL | [http://ir.scsio.ac.cn/handle/344004/9946]  |
| 专题 | 南海海洋研究所_中科院海洋生物资源可持续利用重点实验室 |
| 通讯作者 | wwujun2003@yahoo.com |
| 推荐引用方式 GB/T 7714 | Li, J,Liang, JL,Zhou, Y,et al. Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data[J]. JOURNAL OF SEPARATION SCIENCE,2012,35(7):782-789. |
| APA | Li, J.,Liang, JL.,Zhou, Y.,Wu, J.,Pan, JY.,...&Li, MY.(2012).Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data.JOURNAL OF SEPARATION SCIENCE,35(7),782-789. |
| MLA | Li, J,et al."Identification of the okadaic acid-based toxin profile of a marine dinoflagellate strain Prorocentrum lima by LC-MS/MS and NMR spectroscopic data".JOURNAL OF SEPARATION SCIENCE 35.7(2012):782-789. |
入库方式： OAI收割
来源：南海海洋研究所
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