Glycosides from roots of Cyathula officinalis Kuan
文献类型：期刊论文
| 作者 | Zhou, R ; Li, BG ; Zhang, GL |
| 刊名 | JOURNAL OF INTEGRATIVE PLANT BIOLOGY
 |
| 出版日期 | 2005 |
| 卷号 | 47期号:3页码:368_374 |
| 关键词 | Cyathula officinalis Kuan cytotoxic activity glycoside oleanolic acid |
| ISSN号 | 1672-9072 |
| 产权排序 | 1 |
| 通讯作者 | Zhang, GL, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China. |
| 中文摘要 | To search for new and bioactive compounds from traditional Chinese medicines, a new glycoside, 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-(n-butyl-beta-D-glucopyranosiduronate)]-28-O-beta-D-glucopyranosyl oleanolic acid (1), was isolated from the roots of Cyathula officinalis Kuan, along with 3-O-(methyl-beta-D-glucopyranosiduronate)-28-O-beta-D-glucopyranosyl oleanolic acid (2), 3-O-beta-D-glucopyranosyl oleanolic acid (3), 3-O-beta-D-glucuronopyranosyl oleanolic acid (4), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-(beta-D-glucuronopyranosyl)] oleanolic acid (5), 3-O-(beta-D-glucuronopyranosyl)-28-O-beta-D-glucopyranosyl oleanolic acid (6), 28-O-beta-D-glucuronopyranosyl-(1 -> 4)-beta-D-glucopyranosyl hederagenin (7), 3-O-[alpha-L-rhamnopyranosyl-(1 -> 3)-beta-D-glucuronopyranosyl]-28-O-beta-D-glucopyranosyl oleanolic acid (8), and 3-O-[beta-D-glucopyranosyl-(1 -> 3)-beta-D-glucuronopyranosyl]-28-O-beta-D-glucopyranosyl oleanolic acid (9). The structures of these compounds were determined based on spectral and chemical evidence. The 50 per cent growth-inhibiting (GI(50)) of compounds 1 and 5 against MDA-MB-231 (a human breast cancer cell line) was 3.44 x 10(-4) and 4.66 x 10(-4) mol/L, respectively. |
| 学科主题 | Biochemistry & Molecular Biology; Plant Sciences |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000227555900014 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/17647]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Zhou, R,Li, BG,Zhang, GL. Glycosides from roots of Cyathula officinalis Kuan[J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY,2005,47(3):368_374. |
| APA | Zhou, R,Li, BG,&Zhang, GL.(2005).Glycosides from roots of Cyathula officinalis Kuan.JOURNAL OF INTEGRATIVE PLANT BIOLOGY,47(3),368_374. |
| MLA | Zhou, R,et al."Glycosides from roots of Cyathula officinalis Kuan".JOURNAL OF INTEGRATIVE PLANT BIOLOGY 47.3(2005):368_374. |
入库方式： OAI收割
来源：成都生物研究所
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