A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius
文献类型：期刊论文
| 作者 | Li, LM ; Li, GY ; Xiao, WL ; Zhou, Y ; Li, SH ; Huang, SX ; Han, QB ; Ding, LS ; Lou, LG ; Sun, HD |
| 刊名 | TETRAHEDRON LETTERS
 |
| 出版日期 | 2006 |
| 卷号 | 47期号:29页码:5187_5190 |
| 关键词 | Isodon parvifolius Labiatae parvifolines X and Y NMR data cytotoxicity |
| ISSN号 | 0040-4039 |
| 产权排序 | 2 |
| 通讯作者 | Sun, HD, Chinese Acad Sci, State Key LPhytochem & Plant Resources W China, Kunming Inst Bot, Kunming 650204, Peoples R China. |
| 中文摘要 | Parvifoline X (1), a new rearranged ent-kaurane diterpenoid, and parvifoline Y (2), a new 8,15-seco-ent-kaurane diterpenoid, were isolated from the leaves of Isodon parvifolius. Their structures were elucidated by spectroscopic methods including 2D NMR analysis, and supported by a biogenetic pathway. Parvifoline X (1), possessing a new 15(8 -> 11)-abeo-7 alpha,20-epoxy-entkaurane skeleton, was found from the genus Isodon for the first time. Compounds 1 and 2 were evaluated for their inhibitory activity against A549, HT-29, and K562 cell lines. Parvifoline Y (2) was the most cytotoxic against A549 cells with an IC50 value of 4.97 mu M. (c) 2006 Elsevier Ltd. All rights reserved. |
| 学科主题 | Chemistry, Organic |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000238697600045 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/17757]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Li, LM,Li, GY,Xiao, WL,et al. A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius[J]. TETRAHEDRON LETTERS,2006,47(29):5187_5190. |
| APA | Li, LM.,Li, GY.,Xiao, WL.,Zhou, Y.,Li, SH.,...&Sun, HD.(2006).A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius.TETRAHEDRON LETTERS,47(29),5187_5190. |
| MLA | Li, LM,et al."A new rearranged and a new seco-ent-kaurane diterpenoids from Isodon parvifolius".TETRAHEDRON LETTERS 47.29(2006):5187_5190. |
入库方式： OAI收割
来源：成都生物研究所
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