Probabilistic modeling of aggregate lead exposure in children of urban China using an adapted IEUBK model
文献类型：期刊论文
| 作者 | Zhong, Buqing1; Giubilato, Elisa2; Critto, Andrea2; Wang, Lingqing3 ; Marcomini, Antonio2; Zhang, Jinliang1
|
| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
 |
| 出版日期 | 2017-04-15 |
| 卷号 | 584页码:259-267 |
| 关键词 | Children Lead exposure Blood lead level IEUBK model Source apportionment Exposure pathways |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2016.11.164 |
| 通讯作者 | Zhong, Buqing(zbq0910@163.com) |
| 英文摘要 | Lead, a ubiquitous pollutant throughout the environment, is confirmed to be neurotoxic for children by pulmonary and oral routes. As preschool children in China continue to be exposed to lead, we analyzed the available biomonitoring data for preschool children in urban China collected in the period 2004-2014 through a literature review. To identify apportionment of lead exposure sources for urban children in China, we modified the IEUBK model with a Monte Carlo module to assess the uncertainty and variability of the model output based on limited available exposure data and compared the simulated blood lead levels with the observed ones obtained through literature review. Although children's blood lead levels in urban China decreased statistically over time for the included studies, changes in blood lead levels in three economic zones and seven age groups except for two age specific groups were no longer significant. The GM-predicted BLLs and the GM-observed BLLs agreed within 1 mu g/dL for all fourteen cities. The 95% Cls for the predicted GMs and the observed distribution (GM +/- GSD) overlapped substantially. These results demonstrated the plausibility of blood lead prediction provided by the adapted IEUBK model. Lead exposure estimates for diet, soil/dust, air, and drinking water were 12.01 +/- 6.27 mu g/day, 2.69 +/- 0.89 mu g/day, 0.20 +/- 0.15 mu g/day, and 0.029 +/- 0.012 mu g/day, respectively. These findings showed that the reduction of lead concentrations in grains and vegetables would be beneficial to limit the risk of dietary lead exposure for a large proportion of preschool children in urban China. (C) 2016 Published by Elsevier B.V. |
| WOS关键词 | UPTAKE BIOKINETIC MODEL ; BLOOD LEAD ; PHARMACOKINETIC MODEL ; RISK-ASSESSMENT ; ISOTOPE RATIOS ; YOUNG-CHILDREN ; DIETARY-INTAKE ; KINETIC-MODEL ; HOUSE-DUST ; PB |
| 资助项目 | Ministry of Science and Technology[2012CB525005] ; European Union Seventh Framework Programme (FP7/2007-2013)[269233-GLOCOM] |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:000399358500026 |
| 出版者 | ELSEVIER SCIENCE BV |
| 资助机构 | Ministry of Science and Technology ; European Union Seventh Framework Programme (FP7/2007-2013) |
| 源URL | [http://ir.igsnrr.ac.cn/handle/311030/64562]  |
| 专题 | 中国科学院地理科学与资源研究所 |
| 通讯作者 | Zhong, Buqing |
| 作者单位 | 1.Chinese Res Inst Environm Sci, State Key Lab Environm Criteria & Risk Assessment, Beijing 100012, Peoples R China 2.Univ Ca Foscari Venice, Dept Environm Sci Informat & Stat, Via Torino 155, I-30172 Venice, Italy 3.Chinese Acad Sci, Inst Geog Sci & Nat Resources Res, Key Lab Land Surface Pattern & Simulat, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhong, Buqing,Giubilato, Elisa,Critto, Andrea,et al. Probabilistic modeling of aggregate lead exposure in children of urban China using an adapted IEUBK model[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2017,584:259-267. |
| APA | Zhong, Buqing,Giubilato, Elisa,Critto, Andrea,Wang, Lingqing,Marcomini, Antonio,&Zhang, Jinliang.(2017).Probabilistic modeling of aggregate lead exposure in children of urban China using an adapted IEUBK model.SCIENCE OF THE TOTAL ENVIRONMENT,584,259-267. |
| MLA | Zhong, Buqing,et al."Probabilistic modeling of aggregate lead exposure in children of urban China using an adapted IEUBK model".SCIENCE OF THE TOTAL ENVIRONMENT 584(2017):259-267. |
入库方式： OAI收割
来源：地理科学与资源研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。