Analysis of caged xanthones from the resin of Garcinia hanburyi using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry
文献类型：期刊论文
| 作者 | Zhou, Y ; Liu, X ; Yang, J ; Han, QB ; Song, JZ ; Li, SL ; Qiao, CF ; Ding, LS ; Xu, HX |
| 刊名 | ANALYTICA CHIMICA ACTA
 |
| 出版日期 | 2008 |
| 卷号 | 629期号:1_2页码:104_118 |
| 关键词 | Caged xanthones Fragmentation pathways Computation Garcinia hanburyi Ultra high-performance liquid chromatography (UHPLC) Electrospray ionization quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS/MS) |
| ISSN号 | 0003-2670 |
| 产权排序 | 2 |
| 通讯作者 | Ding, LS, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Sichuan Prov, Peoples R China. |
| 中文摘要 | On-line ultra high-performance liquid chromatography (UHPLC) coupled with electrospray quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS/MS) has been developed for the analysis of a series of caged xanthones in the resin of Garcinia hanburyi. The fragmentation of protonated molecular ions for 12 known cadged xanthones was carried out using low-energy collision-induced electrospray ionization tandem mass spectrometry. It was found that Retro-Diels-Alder rearrangement occurred in the CID processes and produced the characteristic fragment ions, which are especially valuable for the identification of this class of xanthones. The fragmentation differential between some cis-, trans-isomers was uncovered. Computation methods were utilized to rationalize the observed MS behaviors. On-line UHPLC-ESI-MS/MS/MS method has proved to be rapid and efficient in that within 6 min, 15 caged scaffold xanthones, including three pairs of epimers and four pairs of isomers in gamboges, were effectively separated and identified. Among them, two known, namely isogambogenin (13) and isomorellinol (14) and one likely new caged Garcinia xanthones from the Garcinia hanburyi were tentatively characterized based on the tandem mass spectra of known ones. (C) 2008 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry, Analytical |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000260729400012 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/18065]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Zhou, Y,Liu, X,Yang, J,et al. Analysis of caged xanthones from the resin of Garcinia hanburyi using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry[J]. ANALYTICA CHIMICA ACTA,2008,629(1_2):104_118. |
| APA | Zhou, Y.,Liu, X.,Yang, J.,Han, QB.,Song, JZ.,...&Xu, HX.(2008).Analysis of caged xanthones from the resin of Garcinia hanburyi using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry.ANALYTICA CHIMICA ACTA,629(1_2),104_118. |
| MLA | Zhou, Y,et al."Analysis of caged xanthones from the resin of Garcinia hanburyi using ultra-performance liquid chromatography/electrospray ionization quadrupole time-of-flight tandem mass spectrometry".ANALYTICA CHIMICA ACTA 629.1_2(2008):104_118. |
入库方式： OAI收割
来源：成都生物研究所
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