Chemical Fingerprinting of Medicinal Plants "Gui-jiu" by LC-ESI Multiple-Stage MS
文献类型：期刊论文
| 作者 | Zhou, Y ; Jiang, SY ; Ding, LS ; Cheng, SW ; Xu, HX ; But, PPH ; Shaw, PC |
| 刊名 | CHROMATOGRAPHIA
 |
| 出版日期 | 2008 |
| 卷号 | 68期号:9_10页码:781_789 |
| 关键词 | Liquid chromatography-mass spectrometry Electrospray ionization-multiple stage mass spectrometry Chemical fingerprinting Dysosma versipellis Dysosma pleiantha and Sinopodophyllum emodi |
| ISSN号 | 0009-5893 |
| 产权排序 | 2 |
| 通讯作者 | But, PPH, Chinese Univ Hong Kong, Inst Chinese Med, Shatin, Hong Kong, Peoples R China. |
| 中文摘要 | The rhizomes or roots of Dysosma versipellis (Hance) M. Cheng, Dysosma pleiantha (Hance) Woodson, and Sinopodophyllum emodi (Wall. Ex Royle) Ying under the same name "Gui-jiu", were widely used for medicinal purposes. Valid quality control of Gui-jiu is desirable due to the fact that they are highly toxic. In the present paper, an accurate fingerprint method was developed to identify the three species. Liquid chromatography coupled with photodiode array detection and electrospray ionization-multiple stage mass spectrometry were developed to identify the fingerprint components. According to the characteristic fragmentation behavior of known lignans and flavonoids isolated from D. versipellis, a total of 15 constituents in the crude extracts were structurally characterized on the basis of retention time, UV and tandem mass spectrometric analysis. Eight batches of D. versipellis, three batches of D. pleiantha, and two batches of S. emodi were collected from different locations and these representative samples reflected the similar chemical constituent properties. The extracts were separated by a C18 reversed phase LC column, with a gradient solvent system. The proposed method provides a scientific and technical platform to the herbal industry for quality control and safety assurance of herbal preparations that contain this class of poisonous podophyllotoxin-type lignans. |
| 学科主题 | Biochemical Research Methods; Chemistry, Analytical |
| 收录类别 | SCI |
| 资助信息 | Hong Kong Jockey Club Charities Trust Fund |
| 语种 | 英语 |
| WOS记录号 | WOS:000260524400013 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/18071]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Zhou, Y,Jiang, SY,Ding, LS,et al. Chemical Fingerprinting of Medicinal Plants "Gui-jiu" by LC-ESI Multiple-Stage MS[J]. CHROMATOGRAPHIA,2008,68(9_10):781_789. |
| APA | Zhou, Y.,Jiang, SY.,Ding, LS.,Cheng, SW.,Xu, HX.,...&Shaw, PC.(2008).Chemical Fingerprinting of Medicinal Plants "Gui-jiu" by LC-ESI Multiple-Stage MS.CHROMATOGRAPHIA,68(9_10),781_789. |
| MLA | Zhou, Y,et al."Chemical Fingerprinting of Medicinal Plants "Gui-jiu" by LC-ESI Multiple-Stage MS".CHROMATOGRAPHIA 68.9_10(2008):781_789. |
入库方式： OAI收割
来源：成都生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。