Development of an HPLC-DAD-ESI-MSn method for quantitative analysis of Saussurea tridactyla
文献类型：期刊论文
| 作者 | Dawa, Z ; Zhou, Y ; Bai, Y ; Gesang, S ; Bai, BR ; Ding, LS |
| 刊名 | JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
 |
| 出版日期 | 2008 |
| 卷号 | 48期号:4页码:1076_1081 |
| 关键词 | HPLC-DAD-ESI-MSn Identification Content Saussurea tridactyla |
| ISSN号 | 0731-7085 |
| 产权排序 | 1 |
| 通讯作者 | Zhou, Y, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China. |
| 中文摘要 | An improved HPLC-DAD-ESI-MSn method has been developed to simultaneously quantify eight major compounds in Saussurea tridactyla Sch.-Bip. ex Hook. f. which has long been used as a traditional Tibetan medicine. This method was validated to be sensitive, precise and accurate with the LODs of 0.11-5.01 mu g/ml, the overall intra-day and inter-day variations less than 2.70%, and the overall recovery over 98.0%, respectively. The correlation coefficients (r(2)) of the calibration curves were higher than 0.991. This newly established method was successfully applied to reveal the difference in the chemical profiles and contents of these analyses in S. tridactyla from different localities. In addition, by comparison UV and VIS spectra with those of authentic compounds and literatures, a total of fourteen peaks were identified. It can be concluded that this method was effective to ensure the safety and efficacy consistency of S. tridactyla, and can be applied to other traditional Tibetan medicinal plants from different resources in Tibet. (C) 2008 Elsevier B.V. All rights reserved. |
| 学科主题 | Chemistry, Analytical; Pharmacology & Pharmacy |
| 收录类别 | SCI |
| 资助信息 | National Natural Sciences Foundation of China [30450005, 30572254] |
| 语种 | 英语 |
| WOS记录号 | WOS:000262622000004 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/18081]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Dawa, Z,Zhou, Y,Bai, Y,et al. Development of an HPLC-DAD-ESI-MSn method for quantitative analysis of Saussurea tridactyla[J]. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,2008,48(4):1076_1081. |
| APA | Dawa, Z,Zhou, Y,Bai, Y,Gesang, S,Bai, BR,&Ding, LS.(2008).Development of an HPLC-DAD-ESI-MSn method for quantitative analysis of Saussurea tridactyla.JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,48(4),1076_1081. |
| MLA | Dawa, Z,et al."Development of an HPLC-DAD-ESI-MSn method for quantitative analysis of Saussurea tridactyla".JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS 48.4(2008):1076_1081. |
入库方式： OAI收割
来源：成都生物研究所
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