Analysis of Saussurea Species from Tibet Using HPLC-DAD-ESI-MSn
文献类型：期刊论文
| 作者 | Dawa, Z. ; Zhou, Y. ; Bai, Y. ; Gesang, S. ; Liang, J. ; Ding, L. |
| 刊名 | ACTA CHROMATOGRAPHICA
 |
| 出版日期 | 2010 |
| 卷号 | 22期号:1页码:141-152 |
| 关键词 | HPLC-DAD-ESI-MSn analysis flavonoid coumarin Saussurea species Tibet |
| ISSN号 | 1233-2356 |
| 产权排序 | 2 |
| 通讯作者 | Zhou, Y, Chinese Acad Sci, Chengdu Inst Biol, Chengdu 610041, Peoples R China |
| 中文摘要 | An HPLC-DAD-ESI-MSn method has been developed for simultaneous quantification of eight major compounds in eight Saussurea species which have long been used as the traditional Tibetan medicines. The method was validated for sensitivity, precision, and accuracy. LODs were from 0.11 to 5.01 mu g mL(-1), overall intra-day and inter-day variation was less than 2.70%, and overall recovery was over 98.0%. The correlation coefficients (r(2)) of the calibration plots were >0.991. This newly established method was successfully used to reveal difference among the chemical profiles and analytes contents of eight Saussurea species collected in Tibet. In addition, by comparison of UV and mass spectra with those of authentic compounds, a total of fifteen peaks were identified. It can be concluded that this is an effective method for quantification and evaluation of the flavonoids and coumarins in the eight species of the genus Saussurea. It can be used as an efficient reference method for development and use of the eight traditional Tibetan medicines by comparing their different characteristics. |
| 学科主题 | Chemistry, Analytical |
| 收录类别 | SCI |
| 资助信息 | National Key Technology R&D Program of China [2007BAI31B02] |
| 语种 | 英语 |
| WOS记录号 | WOS:000279636600011 |
| 公开日期 | 2011-07-08 |
| 源URL | [http://210.75.237.14/handle/351003/18369]  |
| 专题 | 成都生物研究所_天然产物研究 |
| 推荐引用方式 GB/T 7714 | Dawa, Z.,Zhou, Y.,Bai, Y.,et al. Analysis of Saussurea Species from Tibet Using HPLC-DAD-ESI-MSn[J]. ACTA CHROMATOGRAPHICA,2010,22(1):141-152. |
| APA | Dawa, Z.,Zhou, Y.,Bai, Y.,Gesang, S.,Liang, J.,&Ding, L..(2010).Analysis of Saussurea Species from Tibet Using HPLC-DAD-ESI-MSn.ACTA CHROMATOGRAPHICA,22(1),141-152. |
| MLA | Dawa, Z.,et al."Analysis of Saussurea Species from Tibet Using HPLC-DAD-ESI-MSn".ACTA CHROMATOGRAPHICA 22.1(2010):141-152. |
入库方式： OAI收割
来源：成都生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。