Three new antibacterial active diarylheptanoids from Alpinia officinarum
文献类型:期刊论文
作者 | Zhang, Bei-Bei ; Dai, Yuan ; Liao, Zhi-Xin ; Ding, Li-Sheng |
刊名 | FITOTERAPIA
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出版日期 | 2010 |
卷号 | 81期号:7页码:948-952 |
关键词 | Alpinia officinarum Antibacterial activity Diarylheptanoid |
ISSN号 | 0367-326X |
产权排序 | 2 |
通讯作者 | Liao, ZX, Southeast Univ, Dept Pharmaceut Engn, Sch Chem & Chem Engn, Nanjing 211189, Peoples R China |
中文摘要 | Three new diarylheptanoids, together with ten known ones, were isolated from the ethanol extract from the rhizomes of Alpinia officinarum Hance. The structural identification of these compounds was mainly achieved by spectroscopic methods. The new compounds were elucidated as 7-(4 '', 5 ''-dihydroxy-3 ''-methoxyphenyl)-1-phenyl -4-heptene-3-one (1), 1, 7-diphenyl-5-heptene-3-one (2) and 4-phenethyl-1, 7-diphenyl -1-heptene-3, 5-dione (3), respectively. All of the compounds showed antibacterial activity against Helicobactor pylori. Especially, the three new compounds showed strong antibacterial activity against Hp-Sydney strain 1 with the MIC values of 9-12 mu g/mL, and against Hp-F44 with the MIC values of 2530 mu g/mL. (C) 2010 Elsevier B.V. All rights reserved. |
学科主题 | Chemistry, Medicinal; Pharmacology & Pharmacy |
收录类别 | SCI |
资助信息 | National Natural Science Foundation of China [30770233] |
语种 | 英语 |
WOS记录号 | WOS:000282864800051 |
公开日期 | 2011-07-08 |
源URL | [http://210.75.237.14/handle/351003/18445] ![]() |
专题 | 成都生物研究所_天然产物研究 |
推荐引用方式 GB/T 7714 | Zhang, Bei-Bei,Dai, Yuan,Liao, Zhi-Xin,et al. Three new antibacterial active diarylheptanoids from Alpinia officinarum[J]. FITOTERAPIA,2010,81(7):948-952. |
APA | Zhang, Bei-Bei,Dai, Yuan,Liao, Zhi-Xin,&Ding, Li-Sheng.(2010).Three new antibacterial active diarylheptanoids from Alpinia officinarum.FITOTERAPIA,81(7),948-952. |
MLA | Zhang, Bei-Bei,et al."Three new antibacterial active diarylheptanoids from Alpinia officinarum".FITOTERAPIA 81.7(2010):948-952. |
入库方式: OAI收割
来源:成都生物研究所
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