中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Three new antibacterial active diarylheptanoids from Alpinia officinarum

文献类型:期刊论文

作者Zhang, Bei-Bei ; Dai, Yuan ; Liao, Zhi-Xin ; Ding, Li-Sheng
刊名FITOTERAPIA
出版日期2010
卷号81期号:7页码:948-952
关键词Alpinia officinarum Antibacterial activity Diarylheptanoid
ISSN号0367-326X
产权排序2
通讯作者Liao, ZX, Southeast Univ, Dept Pharmaceut Engn, Sch Chem & Chem Engn, Nanjing 211189, Peoples R China
中文摘要Three new diarylheptanoids, together with ten known ones, were isolated from the ethanol extract from the rhizomes of Alpinia officinarum Hance. The structural identification of these compounds was mainly achieved by spectroscopic methods. The new compounds were elucidated as 7-(4 '', 5 ''-dihydroxy-3 ''-methoxyphenyl)-1-phenyl -4-heptene-3-one (1), 1, 7-diphenyl-5-heptene-3-one (2) and 4-phenethyl-1, 7-diphenyl -1-heptene-3, 5-dione (3), respectively. All of the compounds showed antibacterial activity against Helicobactor pylori. Especially, the three new compounds showed strong antibacterial activity against Hp-Sydney strain 1 with the MIC values of 9-12 mu g/mL, and against Hp-F44 with the MIC values of 2530 mu g/mL. (C) 2010 Elsevier B.V. All rights reserved.
学科主题Chemistry, Medicinal; Pharmacology & Pharmacy
收录类别SCI
资助信息National Natural Science Foundation of China [30770233]
语种英语
WOS记录号WOS:000282864800051
公开日期2011-07-08
源URL[http://210.75.237.14/handle/351003/18445]  
专题成都生物研究所_天然产物研究
推荐引用方式
GB/T 7714
Zhang, Bei-Bei,Dai, Yuan,Liao, Zhi-Xin,et al. Three new antibacterial active diarylheptanoids from Alpinia officinarum[J]. FITOTERAPIA,2010,81(7):948-952.
APA Zhang, Bei-Bei,Dai, Yuan,Liao, Zhi-Xin,&Ding, Li-Sheng.(2010).Three new antibacterial active diarylheptanoids from Alpinia officinarum.FITOTERAPIA,81(7),948-952.
MLA Zhang, Bei-Bei,et al."Three new antibacterial active diarylheptanoids from Alpinia officinarum".FITOTERAPIA 81.7(2010):948-952.

入库方式: OAI收割

来源:成都生物研究所

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