Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin
文献类型：期刊论文
| 作者 | Xiong, Jie1,2; Gao, Shan3,4; Dui, Wen1; Yang, Wentao2; Chen, Xiao3; Taverna, Sean D.5,6; Pearlman, Ronald E.7; Ashlock, Wendy7; Miao, Wei2; Liu, Yifan1 |
| 刊名 | NUCLEIC ACIDS RESEARCH
 |
| 出版日期 | 2016-12-01 |
| 卷号 | 44期号:21页码:10091-10105 |
| ISSN号 | 0305-1048 |
| DOI | 10.1093/nar/gkw684 |
| 英文摘要 | The ciliate protozoan Tetrahymena thermophila contains two types of structurally and functionally differentiated nuclei: the transcriptionally active somatic macronucleus (MAC) and the transcriptionally silent germ-line micronucleus (MIC). Here, we demonstrate that MAC features well-positioned nucleosomes downstream of transcription start sites and flanking splice sites. Transcription-associated trans-determinants promote nucleosome positioning in MAC. By contrast, nucleosomes in MIC are dramatically delocalized. Nucleosome occupancy in MAC and MIC are nonetheless highly correlated with each other, as well as with in vitro reconstitution and predictions based upon DNA sequence features, revealing unexpectedly strong contributions from cis-determinants. In particular, well-positioned nucleosomes are often matched with GC content oscillations. As many nucleosomes are coordinately accommodated by both cis- and trans-determinants, we propose that their distribution is shaped by the impact of these nucleosomes on the mutational and transcriptional landscape, and driven by evolutionary selection. |
| WOS关键词 | BASE-PAIR RESOLUTION ; SACCHAROMYCES-CEREVISIAE ; EUKARYOTIC GENOME ; DNA ELIMINATION ; HISTONE H3 ; NUCLEAR DEVELOPMENT ; START SITES ; R PACKAGE ; IN-VIVO ; ORGANIZATION |
| 资助项目 | Natural Science Foundation of China[31301930] ; Natural Science Foundation of China[31522051] ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH[R01 GM106024] ; NIH[R01 GM087343] ; Canadian Institutes of Health Research[MOP13347] ; Natural Sciences and Engineering Research Council of Canada[53909] ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China[2013DFG32390] ; NSF[MCB 1411565] ; Department of Pathology at the University of Michigan |
| WOS研究方向 | Biochemistry & Molecular Biology |
| 语种 | 英语 |
| WOS记录号 | WOS:000393979400012 |
| 出版者 | OXFORD UNIV PRESS |
| 资助机构 | Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Natural Science Foundation of China ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Knowledge Innovation Programof the Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, China ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; NIH ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Canadian Institutes of Health Research ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Natural Sciences and Engineering Research Council of Canada ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; Projects of International Cooperation and Exchanges, Ministry of Science and Technology of China ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; NSF ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan ; Department of Pathology at the University of Michigan |
| 源URL | [http://ir.ihb.ac.cn/handle/342005/33057]  |
| 专题 | 水生生物研究所_水生生物分子与细胞生物学研究中心_期刊论文 |
| 通讯作者 | Miao, Wei; Liu, Yifan |
| 作者单位 | 1.Univ Michigan, Dept Pathol, Ann Arbor, MI 48109 USA 2.Chinese Acad Sci, Inst Hydrobiol, Key Lab Aquat Biodivers & Conservat, Wuhan 430072, Peoples R China 3.Ocean Univ China, Inst Evolut & Marine Biodivers, Qingdao 266003, Peoples R China 4.Qingdao Natl Lab Marine Sci & Technol, Lab Marine Biol & Biotechnol, Qingdao 266003, Peoples R China 5.Johns Hopkins Univ, Sch Med, Dept Pharmacol & Mol Sci, Baltimore, MD 21205 USA 6.Johns Hopkins Univ, Sch Med, Ctr Epigenet, Baltimore, MD 21205 USA 7.York Univ, Dept Biol, Toronto, ON M3J 1P3, Canada |
| 推荐引用方式 GB/T 7714 | Xiong, Jie,Gao, Shan,Dui, Wen,et al. Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin[J]. NUCLEIC ACIDS RESEARCH,2016,44(21):10091-10105. |
| APA | Xiong, Jie.,Gao, Shan.,Dui, Wen.,Yang, Wentao.,Chen, Xiao.,...&Liu, Yifan.(2016).Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin.NUCLEIC ACIDS RESEARCH,44(21),10091-10105. |
| MLA | Xiong, Jie,et al."Dissecting relative contributions of cis- and trans-determinants to nucleosome distribution by comparing Tetrahymena macronuclear and micronuclear chromatin".NUCLEIC ACIDS RESEARCH 44.21(2016):10091-10105. |
入库方式： OAI收割
来源：水生生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。