A water-soluble AIE-active polyvalent glycocluster: design, synthesis and studies on carbohydrate-lectin interactions for visualization of Siglec distributions in living cell membranes
文献类型：期刊论文
| 作者 | Liu, Guang-jian; Zhang, Yuan; Zhou, Lingyun; Jia, Li-yan; Jiang, Guohua; Xing, Guo-wen; Wang, Shu |
| 刊名 | CHEMICAL COMMUNICATIONS
 |
| 出版日期 | 2019-08-25 |
| 卷号 | 55期号:66页码:9869-9872 |
| ISSN号 | 1359-7345 |
| DOI | 10.1039/c9cc05008f |
| 英文摘要 | In this work, we designed and synthesized an aggregation-induced emission (AIE)-active tetraphenylethene-decorated pseudo-trisialic acid (TPE3S) and validated its high affinity for Siglecs using microscale thermophoresis techniques. TPE3S was a unique binding-on fluorescent trivalent sialocluster which was successfully utilized for the visualization of Siglecs expressed on the surface of mammalian cells. |
| 语种 | 英语 |
| WOS记录号 | WOS:000480589900026 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/82639]  |
| 专题 | 中国科学院化学研究所 |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Guang-jian,Zhang, Yuan,Zhou, Lingyun,et al. A water-soluble AIE-active polyvalent glycocluster: design, synthesis and studies on carbohydrate-lectin interactions for visualization of Siglec distributions in living cell membranes[J]. CHEMICAL COMMUNICATIONS,2019,55(66):9869-9872. |
| APA | Liu, Guang-jian.,Zhang, Yuan.,Zhou, Lingyun.,Jia, Li-yan.,Jiang, Guohua.,...&Wang, Shu.(2019).A water-soluble AIE-active polyvalent glycocluster: design, synthesis and studies on carbohydrate-lectin interactions for visualization of Siglec distributions in living cell membranes.CHEMICAL COMMUNICATIONS,55(66),9869-9872. |
| MLA | Liu, Guang-jian,et al."A water-soluble AIE-active polyvalent glycocluster: design, synthesis and studies on carbohydrate-lectin interactions for visualization of Siglec distributions in living cell membranes".CHEMICAL COMMUNICATIONS 55.66(2019):9869-9872. |
入库方式： OAI收割
来源：化学研究所
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