Direct detection of potassium and lead (II) ions based on assembly- disassembly of a chiral cyanine dye /TBA complex
文献类型：期刊论文
| 作者 | Shen, Gang; Zhang, Hong; Xiang, Junfeng; Yang, Fengmin; Wu, Shuling; Wang, Wei; Du, Ning; Zhang, Jinghua; Sun, Tao; Tang, Yalin |
| 刊名 | TALANTA
 |
| 出版日期 | 2019-08-15 |
| 卷号 | 201页码:490-495 |
| ISSN号 | 0039-9140 |
| DOI | 10.1016/j.talanta.2019.04.032 |
| 英文摘要 | A highly selective and sensitive direct detection of potassium (K+) and lead (Pb2+) ions was developed by using the assembly and disassembly of a chiral cyanine dye/TBA complex. The dye DMSB (3-ethyl-2-[3-(3-ethyl-3H-benzoselenazol-2-ylidene)-2-methylprop-1-enyl] benzoselenazolium bromide) loses the ability of self-assembly, but it can be activated by thrombin-binding aptamer (TBA) G-quadruplex structure. And only the TBA G-quadruplex formed in the presence of K + , can strongly induce J-aggregate signals of DMSB. Because the Pb2+ ions can bind and stabilize the TBA G-quadruplex with much higher efficiency than K+, the J-aggregate signals of DMSB falls sharply when the Pb2+ is present. As a result, the assembly and disassembly of DMSB allows the selective detection of 10 mu M K+ and 20 nM Pb2+ respectively, even the competitive sodium ion (Na+) was as high as 145 mM. The linear correlation existed between the J-aggregate intensity and the concentration of K+ and Pb2+ over the range of 0.5-5.0 mM and 200-2000 nM, respectively. Moreover, the concentration of K+ (similar to 3 mM) and Pb2+ (below 20 nM) in human blood serum samples were determined by the present method, which agreed well with inductively coupled plasma mass spectrometry (ICP-MS). This work not only opens a door for the further development of G-quadruplex-based aptasensor in complex real system, but also provides a simple and versatile sensing platform for ion detection in clinic. |
| 语种 | 英语 |
| WOS记录号 | WOS:000471084300066 |
| 源URL | [http://ir.iccas.ac.cn/handle/121111/82660]  |
| 专题 | 中国科学院化学研究所 |
| 作者单位 | Chinese Acad Sci, Inst Chem, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Shen, Gang,Zhang, Hong,Xiang, Junfeng,et al. Direct detection of potassium and lead (II) ions based on assembly- disassembly of a chiral cyanine dye /TBA complex[J]. TALANTA,2019,201:490-495. |
| APA | Shen, Gang.,Zhang, Hong.,Xiang, Junfeng.,Yang, Fengmin.,Wu, Shuling.,...&Tang, Yalin.(2019).Direct detection of potassium and lead (II) ions based on assembly- disassembly of a chiral cyanine dye /TBA complex.TALANTA,201,490-495. |
| MLA | Shen, Gang,et al."Direct detection of potassium and lead (II) ions based on assembly- disassembly of a chiral cyanine dye /TBA complex".TALANTA 201(2019):490-495. |
入库方式： OAI收割
来源：化学研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。