Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries
文献类型：期刊论文
| ; | |
| 作者 | Rentschler, G; Rodushkin, I; Cerna, M; Chen, CY; Harari, F; Harari, R; Horvat, M; Hruba, F; Kasparova, L; Koppova, K |
| 刊名 | INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
 ; INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
|
| 出版日期 | 2018 ; 2018 |
| 卷号 | 221期号:2页码:223-230 |
| 关键词 | Catalytic converters Catalytic converters Traffic Cis-platinum Human Biomarkers Biomonitoring Metals Women High-resolution ICP-MS Traffic Cis-platinum Human Biomarkers Biomonitoring Metals Women High-resolution ICP-MS |
| ISSN号 | 1438-4639 ; 1438-4639 |
| DOI | 10.1016/j.ijheh.2017.10.017 ; 10.1016/j.ijheh.2017.10.017 |
| 文献子类 | Article ; Article |
| 英文摘要 | Background: There is little reliable information on human exposure to the metals platinum (Pt), palladium (Pd) and rhodium (Rh), despite their use in enormous quantities in catalytic converters for automobile exhaust systems. Objectives: To evaluate blood concentrations of Pt (B-Pt), Pd (B-Pd) and Rh (B-Rh) in women from six European and three non-European countries, and to identify potentially influential factors. In addition, molybdenum (Mo) and strontium (Sr) were analysed. Methods: Blood from 248 women aged 47-61 was analysed by high resolution inductively coupled plasma mass spectrometry under strict quality control. Results: The medians were: B-Pt 0.8 (range < 0.6-5.2), B-Pd < 5 (< 5-9.3), B-Rh < 0.4 (< 0.4-3.6) ng/L and BMo 2.0 (0.2-16) and B-Sr 16.6 (3.5-49) pg/L. Two women with highly elevated B-Pt (242 and 60 ng/L), previously cancer treated with cis-platinum, were not included in the data analysis. All elements varied geographically (2-3 times) (B-Pd P = 0.05; all other elements P < 0.001); variations within each area were generally 5-10 times. Traffic was not associated with increased concentrations. Conclusions: General population blood concentrations of Pt, Pd and Rh are within or below the single digit ng/L range, much lower than in most previous reports. This is probably due to improved analytical performance, allowing for more reliable information at ultra-trace levels. In general, Mo and Sr agreed with previously reported concentrations. All elements showed geographical and inter-individual variations, but no convincing relationships with self-reported traffic intensity were found. Pt from the antineoplastic drug cis-platinum it retained in the body for years.; Background: There is little reliable information on human exposure to the metals platinum (Pt), palladium (Pd) and rhodium (Rh), despite their use in enormous quantities in catalytic converters for automobile exhaust systems. Objectives: To evaluate blood concentrations of Pt (B-Pt), Pd (B-Pd) and Rh (B-Rh) in women from six European and three non-European countries, and to identify potentially influential factors. In addition, molybdenum (Mo) and strontium (Sr) were analysed. Methods: Blood from 248 women aged 47-61 was analysed by high resolution inductively coupled plasma mass spectrometry under strict quality control. Results: The medians were: B-Pt 0.8 (range < 0.6-5.2), B-Pd < 5 (< 5-9.3), B-Rh < 0.4 (< 0.4-3.6) ng/L and BMo 2.0 (0.2-16) and B-Sr 16.6 (3.5-49) pg/L. Two women with highly elevated B-Pt (242 and 60 ng/L), previously cancer treated with cis-platinum, were not included in the data analysis. All elements varied geographically (2-3 times) (B-Pd P = 0.05; all other elements P < 0.001); variations within each area were generally 5-10 times. Traffic was not associated with increased concentrations. Conclusions: General population blood concentrations of Pt, Pd and Rh are within or below the single digit ng/L range, much lower than in most previous reports. This is probably due to improved analytical performance, allowing for more reliable information at ultra-trace levels. In general, Mo and Sr agreed with previously reported concentrations. All elements showed geographical and inter-individual variations, but no convincing relationships with self-reported traffic intensity were found. Pt from the antineoplastic drug cis-platinum it retained in the body for years. |
| 电子版国际标准刊号 | 1618-131X ; 1618-131X |
| WOS关键词 | PLASMA-MASS SPECTROMETRY ; PLASMA-MASS SPECTROMETRY ; CATALYST PRODUCTION PLANT ; TRACE-ELEMENTS ; WHOLE-BLOOD ; SWEDISH ADOLESCENTS ; GROUP METALS ; ICP-MS ; EXPOSURE ; URINE ; POPULATION ; CATALYST PRODUCTION PLANT ; TRACE-ELEMENTS ; WHOLE-BLOOD ; SWEDISH ADOLESCENTS ; GROUP METALS ; ICP-MS ; EXPOSURE ; URINE ; POPULATION |
| WOS研究方向 | Public, Environmental & Occupational Health ; Public, Environmental & Occupational Health ; Infectious Diseases ; Infectious Diseases |
| 语种 | 英语 ; 英语 |
| WOS记录号 | WOS:000429397300008 ; WOS:000429397300008 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/285801]  |
| 专题 | 高能物理研究所_多学科研究中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Rentschler, G,Rodushkin, I,Cerna, M,et al. Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries, Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries[J]. INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,2018, 2018,221, 221(2):223-230, 223-230. |
| APA | Rentschler, G.,Rodushkin, I.,Cerna, M.,Chen, CY.,Harari, F.,...&李玉锋.(2018).Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries.INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH,221(2),223-230. |
| MLA | Rentschler, G,et al."Platinum, palladium, rhodium, molybdenum and strontium in blood of urban women in nine countries".INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH 221.2(2018):223-230. |
入库方式： OAI收割
来源：高能物理研究所
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