Three-dimensional angiography fused with CT/MRI for multimodal imaging of nanoparticles based on Ba4Yb3F17:Lu3+,Gd3+
文献类型：期刊论文
| 作者 | Lei, RH; Li, GP; Xin, GM; Li, J ; Mei, LQ; Kong, JL; Qin, YX; Yin, WY; Xia, SB; Zhang, JX
|
| 刊名 | NANOSCALE
 |
| 出版日期 | 2018 |
| 卷号 | 10期号:28页码:13402-13409 |
| ISSN号 | 2040-3364 |
| DOI | 10.1039/c8nr03054e |
| 文献子类 | Article |
| 英文摘要 | Designing nanosized multi-modality contrast agents for high-resolution imaging is challenging since most agents are only useful for single-mode imaging. In this work, we successfully synthesized biocompatible polyethylene glycol (PEG-) and l-glutamine (GLN-) modified Ba4Yb3F17:Lu3+,Gd3+ nanoparticles (LNPs@PEG@GLN) that can be employed as a multi-modality contrast agent. Fluorescence dye-modified LNPs@PEG@GLN nanoparticles can be used for computed tomography (CT), magnetic resonance imaging (MRI), and fluorescence imaging (FI). They display high X-ray absorption, outstanding T-2-weighted imaging capability, and good fluorescence uptake. Furthermore, LNPs@PEG@GLN enhances contrast efficiencies for different imaging modalities in vivo. Interestingly, LNPs@PEG@GLN is a promising agent for CT angiography. These nanoparticles could be a promising contrast agent for multi-modality imaging and diagnosing vascular diseases. |
| 电子版国际标准刊号 | 2040-3372 |
| WOS关键词 | RAY COMPUTED-TOMOGRAPHY ; UP-CONVERSION NANOPARTICLES ; BINARY CONTRAST AGENT ; IN-VIVO ; CT ; NANOPHOSPHORS ; NANOCRYSTALS ; LUMINESCENCE ; MRI ; ANGIOGENESIS |
| WOS研究方向 | Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:000439319000013 |
| 源URL | [http://ir.ihep.ac.cn/handle/311005/286142]  |
| 专题 | 高能物理研究所_多学科研究中心 高能物理研究所_加速器中心 |
| 作者单位 | 中国科学院高能物理研究所 |
| 推荐引用方式 GB/T 7714 | Lei, RH,Li, GP,Xin, GM,et al. Three-dimensional angiography fused with CT/MRI for multimodal imaging of nanoparticles based on Ba4Yb3F17:Lu3+,Gd3+[J]. NANOSCALE,2018,10(28):13402-13409. |
| APA | Lei, RH.,Li, GP.,Xin, GM.,Li, J.,Mei, LQ.,...&马思汉.(2018).Three-dimensional angiography fused with CT/MRI for multimodal imaging of nanoparticles based on Ba4Yb3F17:Lu3+,Gd3+.NANOSCALE,10(28),13402-13409. |
| MLA | Lei, RH,et al."Three-dimensional angiography fused with CT/MRI for multimodal imaging of nanoparticles based on Ba4Yb3F17:Lu3+,Gd3+".NANOSCALE 10.28(2018):13402-13409. |
入库方式： OAI收割
来源：高能物理研究所
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