Electroacupuncture Modulates Resting-State Functional Connectivity in the Default Mode Network for Healthy Older Adults
文献类型：期刊论文
| 作者 | Fan, Dong-qiong1,2; Zhao, Hai-chao2; Sheng, Jing1; Liu, Yun-rui1; Yu, Jing1,3
|
| 刊名 | JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY
 |
| 出版日期 | 2019-08-13 |
| 页码 | 8 |
| 关键词 | electroacupuncture older adults resting state functional connectivity default mode network |
| ISSN号 | 0891-9887 |
| DOI | 10.1177/0891988719868304 |
| 通讯作者 | Yu, Jing(helen12@swu.edu.cn) |
| 英文摘要 | Aging involves cognitive decline and prominent alterations in brain activity. Electroacupuncture (EA), a traditional Chinese medicine approach, is demonstrated to be effective in improving cognitive function of older adults. However, the specific neural mechanism underlying this modulation effect remains unclear. In this study, we used functional magnetic resonance imaging (fMRI) to investigate whether EA could improve cognitive performance of community-dwelling older adults and whether these potential improvements are associated with the EA-induced brain functional connectivity alterations. Thirty healthy older adults were recruited and randomly assigned to the EA group and the control group. Behaviorally, we observed an EA-induced improvement in cognitive performance of older adults in the Montreal Cognitive Assessment. On a neural perspective, the EA intervention significantly increased the functional connectivity within the default mode network. Moreover, we found a positive association between the improvement in delayed memory performance and the alterations in the ventral medial prefrontal cortex-hippocampal formation connectivity in the EA group. This study extends previous findings by showing that healthy older adults exhibit neural plasticity manifested as increased functional connectivity after EA sessions, which could induce therapeutic effects in the treatment of neurodegenerative diseases. |
| WOS关键词 | MILD COGNITIVE IMPAIRMENT ; NONINVASIVE BRAIN-STIMULATION ; BRIEF SCREENING TOOL ; ALZHEIMERS-DISEASE ; ACUPUNCTURE STIMULATION ; METABOLISM ; VERSION |
| 资助项目 | National Natural Science Foundation of China[31300856] ; Ministry of Education of Humanities and Social Science project[17YJA190015] ; CAS Key Laboratory of Mental Health, Institute of Psychology[KLMH2019K02] ; Fundamental Research Funds for the Central Universities[SWU1709221] |
| WOS研究方向 | Geriatrics & Gerontology ; Neurosciences & Neurology ; Psychiatry |
| 语种 | 英语 |
| WOS记录号 | WOS:000483173400001 |
| 出版者 | SAGE PUBLICATIONS INC |
| 资助机构 | National Natural Science Foundation of China ; Ministry of Education of Humanities and Social Science project ; CAS Key Laboratory of Mental Health, Institute of Psychology ; Fundamental Research Funds for the Central Universities |
| 源URL | [http://ir.psych.ac.cn/handle/311026/29821]  |
| 专题 | 心理研究所_中国科学院心理健康重点实验室 |
| 通讯作者 | Yu, Jing |
| 作者单位 | 1.Southwest Univ, Fac Psychol, Tiansheng Rd, Chongqing 400715, Peoples R China 2.Beihang Univ, Sch Biol Sci & Med Engn, Beijing, Peoples R China 3.Inst Psychol, CAS Key Lab Mental Hlth, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fan, Dong-qiong,Zhao, Hai-chao,Sheng, Jing,et al. Electroacupuncture Modulates Resting-State Functional Connectivity in the Default Mode Network for Healthy Older Adults[J]. JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY,2019:8. |
| APA | Fan, Dong-qiong,Zhao, Hai-chao,Sheng, Jing,Liu, Yun-rui,&Yu, Jing.(2019).Electroacupuncture Modulates Resting-State Functional Connectivity in the Default Mode Network for Healthy Older Adults.JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY,8. |
| MLA | Fan, Dong-qiong,et al."Electroacupuncture Modulates Resting-State Functional Connectivity in the Default Mode Network for Healthy Older Adults".JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY (2019):8. |
入库方式： OAI收割
来源：心理研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。