中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
Surface-based regional homogeneity in bipolar disorder: A resting-state fMRI study

文献类型:期刊论文

作者Zhang Bo1; Wang Fei2,3; Dong Hao-Ming; Jiang Xiao-Wei2; Wei Sheng-Nan2; Chang Miao2; Yin Zhi-Yang2; Yang Ning3; Zuo Xi-Nian3,4,5; Tang Yan-Qing2
刊名PSYCHIATRY RESEARCH
出版日期2019-08-01
卷号278页码:199-204
ISSN号0165-1781
关键词Ventral visual stream Regional homogeneity Bipolar disorder Functional magnetic resonance imaging
DOI10.1016/j.psychres.2019.05.045
产权排序4
文献子类article
英文摘要

Surface-based, two-dimensional regional homogeneity (2dReHo) was used in the current study to compare local functional synchronization of spontaneous neuronal activity between patients with bipolar disorder (BD) and healthy controls (HC), rather than volume-based, three-dimensional regional homogeneity (3dReHo) methods that have been previously described. Seventy-one BD patients and 113 HC participated in structural and resting-state fMRI scans. Participants ranged in age from 12 to 54 years. All subjects were rated with the Young Mania Rating Scale and the Hamilton Depression Rating Scale. BD patients showed reduced surface-based ReHo across the cortical surface, both at the global level and in the left ventral visual stream (VVS). Additionally, ReHo value across the cortical surface showed a significant negative correlation with age in both groups at the global level. Abnormal activity in the left VVS cortex may contribute to the pathogenesis of BD. Therefore, surface-based ReHo may be a useful index to explore the pathophysiology of BD.

WOS关键词SCHIZOPHRENIA ; FRAMEWORK ; NETWORK
资助项目National Natural Science Foundation of China[81271499] ; National Natural Science Foundation of China[81571331] ; National Key Research and Development Program[2016YFC1306900] ; National Key Research and Development Program[2016YFC 0904300] ; National High Tech Development Plan (863)[2015AA020513]
WOS研究方向Psychiatry
语种英语
出版者ELSEVIER IRELAND LTD
WOS记录号WOS:000477689600027
资助机构National Natural Science Foundation of China ; National Key Research and Development Program ; National High Tech Development Plan (863)
源URL[http://ir.psych.ac.cn/handle/311026/29582]  
专题心理研究所_中国科学院行为科学重点实验室
通讯作者Xu Ke
作者单位1.China Med Univ, Hosp 1, Dept Radiol, 155 Nanjing North St, Shenyang 110001, Liaoning, Peoples R China
2.China Med Univ, Hosp 1, Dept Radiol & Psychiat, 155 Nanjing North St, Shenyang 110001, Liaoning, Peoples R China
3.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China
4.Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China
5.Chinese Acad Sci, Inst Psychol, Magnet Resonance Imaging Res Ctr, Beijing 100101, Peoples R China
推荐引用方式
GB/T 7714
Zhang Bo,Wang Fei,Dong Hao-Ming,et al. Surface-based regional homogeneity in bipolar disorder: A resting-state fMRI study[J]. PSYCHIATRY RESEARCH,2019,278:199-204.
APA Zhang Bo.,Wang Fei.,Dong Hao-Ming.,Jiang Xiao-Wei.,Wei Sheng-Nan.,...&Xu Ke.(2019).Surface-based regional homogeneity in bipolar disorder: A resting-state fMRI study.PSYCHIATRY RESEARCH,278,199-204.
MLA Zhang Bo,et al."Surface-based regional homogeneity in bipolar disorder: A resting-state fMRI study".PSYCHIATRY RESEARCH 278(2019):199-204.

入库方式: OAI收割

来源:心理研究所

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