Optimization of medium composition for butyric acid production by Clostridium thermobutyricum using response surface methodology
文献类型：期刊论文
| 作者 | Zhang, Chun-Hui1,2; Ma, Yu-Jiu1; Yang, Fang-Xiao1; Liu, Wei1; Zhang, Yue-Dong1 |
| 刊名 | BIORESOURCE TECHNOLOGY
 |
| 出版日期 | 2009-09-01 |
| 卷号 | 100期号:18页码:4284-4288 |
| 关键词 | Clostridium thermobutyricum Butyric acid Response surface methodology |
| 中文摘要 | The optimal medium for butyric acid production by Clostridium thermobutyricum in a shake flask culture was studied using statistical experimental design and analysis. The optimal composition of the fermentation medium for maximum butyric acid yield, as determined on the basis of a three-level four-factor Box-Behnken design (BBD), was obtained by response surface methodology (RSM). The high correlation between the predicted and observed values indicated the validity of the model. A maximum butyric acid yield of 12.05 g/l was obtained at K(2)HPO(4) 7.2 g/l, 34.9 g/l glucose. 20 g/l yeast extract, and 15 g/l acetate, which compared well to the predicated production of 12.13 g/l. |
| 英文摘要 | The optimal medium for butyric acid production by Clostridium thermobutyricum in a shake flask culture was studied using statistical experimental design and analysis. The optimal composition of the fermentation medium for maximum butyric acid yield, as determined on the basis of a three-level four-factor Box-Behnken design (BBD), was obtained by response surface methodology (RSM). The high correlation between the predicted and observed values indicated the validity of the model. A maximum butyric acid yield of 12.05 g/l was obtained at K(2)HPO(4) 7.2 g/l, 34.9 g/l glucose. 20 g/l yeast extract, and 15 g/l acetate, which compared well to the predicated production of 12.13 g/l. (C) 2009 Published by Elsevier Ltd. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine ; Technology |
| 学科主题 | 公共技术 |
| 类目[WOS] | Agricultural Engineering ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| 研究领域[WOS] | Agriculture ; Biotechnology & Applied Microbiology ; Energy & Fuels |
| 关键词[WOS] | TYROBUTYRICUM ; FERMENTATION ; CULTURE ; MECHANISMS ; ACETATE ; GLUCOSE ; DESIGN ; MUTANT |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000266964400034 |
| 公开日期 | 2011-09-09 |
| 源URL | [http://ir.qibebt.ac.cn//handle/337004/362]  |
| 专题 | 青岛生物能源与过程研究所_技术转移部中试技术服务中心 |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Biefuel, Qingdao Inst Bioenergy & Bioproc Technol, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Grad Univ, Beijing, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Chun-Hui,Ma, Yu-Jiu,Yang, Fang-Xiao,et al. Optimization of medium composition for butyric acid production by Clostridium thermobutyricum using response surface methodology[J]. BIORESOURCE TECHNOLOGY,2009,100(18):4284-4288. |
| APA | Zhang, Chun-Hui,Ma, Yu-Jiu,Yang, Fang-Xiao,Liu, Wei,&Zhang, Yue-Dong.(2009).Optimization of medium composition for butyric acid production by Clostridium thermobutyricum using response surface methodology.BIORESOURCE TECHNOLOGY,100(18),4284-4288. |
| MLA | Zhang, Chun-Hui,et al."Optimization of medium composition for butyric acid production by Clostridium thermobutyricum using response surface methodology".BIORESOURCE TECHNOLOGY 100.18(2009):4284-4288. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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