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Biosynthetic pathways for 3-hydroxypropionic acid production
文献类型：期刊论文
| 作者 | Jiang, Xinglin; Meng, Xin; Xian, Mo
|
| 刊名 | APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
 |
| 出版日期 | 2009-04-01 |
| 卷号 | 82期号:6页码:995-1003 |
| 关键词 | 3-Hydroxypropionic acid Pathway Fermentation Thermodynamics |
| ISSN号 | ISSN: 1432-0614 |
| 中文摘要 | Biobased platform chemicals have attracted growing interest recently. Among them, 3-hydroxypropionic acid receives significant attention due to its applications in the synthesis of novel polymer materials and other derivatives. To establish a biotechnology route instead of the problematic chemical synthesis of 3-hydroxypropionic acid, biosynthetic pathway is required, and the strategies of how to engineer a microbe to produce this product should be considered. In the present review, we summarize and review all known pathways, which could be potentially constructed for 3-hydroxypropionic acid production. Mass and redox balances are discussed in detail. Thermodynamic favorability is evaluated by standard Gibbs free energy. The assembly of pathways and possible solutions are proposed. Several new techniques and future research needs are also covered. |
| 英文摘要 | Biobased platform chemicals have attracted growing interest recently. Among them, 3-hydroxypropionic acid receives significant attention due to its applications in the synthesis of novel polymer materials and other derivatives. To establish a biotechnology route instead of the problematic chemical synthesis of 3-hydroxypropionic acid, biosynthetic pathway is required, and the strategies of how to engineer a microbe to produce this product should be considered. In the present review, we summarize and review all known pathways, which could be potentially constructed for 3-hydroxypropionic acid production. Mass and redox balances are discussed in detail. Thermodynamic favorability is evaluated by standard Gibbs free energy. The assembly of pathways and possible solutions are proposed. Several new techniques and future research needs are also covered. |
| WOS标题词 | Science & Technology ; Life Sciences & Biomedicine |
| 学科主题 | 生物基化学品 |
| 类目[WOS] | Biotechnology & Applied Microbiology |
| 研究领域[WOS] | Biotechnology & Applied Microbiology |
| 关键词[WOS] | AUTOTROPHIC CO2 FIXATION ; BETA-HYDROXYPROPIONIC ACID ; CHLOROFLEXUS-AURANTIACUS ; ACRYLIC-ACID ; KLEBSIELLA-PNEUMONIAE ; KEY ENZYME ; GLYCEROL ; FERMENTATION ; CYCLE ; 1,3-PROPANEDIOL |
| 收录类别 | SCI |
| 语种 | 英语 |
| WOS记录号 | WOS:000265382200001 |
| 公开日期 | 2011-09-09 |
| 源URL | [http://ir.qibebt.ac.cn//handle/337004/446]  |
| 专题 | 青岛生物能源与过程研究所_材料生物技术研究中心 |
| 作者单位 | Chinese Acad Sci, Qingdao Inst Biomass Energy & Bioproc Technol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Xinglin,Meng, Xin,Xian, Mo. Biosynthetic pathways for 3-hydroxypropionic acid production[J]. APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,2009,82(6):995-1003. |
| APA | Jiang, Xinglin,Meng, Xin,&Xian, Mo.(2009).Biosynthetic pathways for 3-hydroxypropionic acid production.APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,82(6),995-1003. |
| MLA | Jiang, Xinglin,et al."Biosynthetic pathways for 3-hydroxypropionic acid production".APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 82.6(2009):995-1003. |
入库方式： OAI收割
来源：青岛生物能源与过程研究所
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